Introduction The purpose of this white paper is to review the currently available scientific evidence related to nutrition and hydration for pressure ulcer prevention and treatment in adults; introduce the nutrition recommendations from the new National Pressure Ulcer Advisory Panel (NPUAP)-European Pressure Ulcer Advisory Panel (EPUAP) Guidelines for Pressure Ulcer Treatment; and review resear...

Ulcer is a common problem associated with NSAID’s use. The use of plants to treat and cure diseases is common practice since ancient times because of people blind faith on safety of plant’s use. The present study aimed to evaluate anti-ulcer activity of Dalbergia sissoo in alcohol and aspirin induced ulcerative rat models. Animals were divided into four groups. Group I was disease control, grou...

BACKGROUND Ulcer type and non-ulcer type interstitial cystitis/bladder pain syndromes (IC/BPS) are considered different disease entities. Thus, intravesical botulinum toxin A (BoNT-A) treatment outcomes could differ for each entity. OBJECTIVES To evaluate and compare the treatment outcomes of BoNT-A injections for treatment of each IC/BPS type. STUDY DESIGN Prospective interventional study....

OBJECTIVE Helicobacter pylori infection is a very common infection worldwide particularly in the developing countries. The organism plays an important role in peptic ulcer diseases. The aim of the study was to detect and correlate the prevalence of Helicobacter pylori with such diseases and to evaluate the histopathological grading of gastritis. METHODS One hundred thirty two patients of 15-8...

Ficus religiosa is being used in Ayurvedic and Malay traditional medicine for the treatment of various diseases including gastric ulcer. Considering the above claims, the present work was undertaken to validate the anti-ulcer potential of the ethanol extract of leaves of Ficus religiosa against in vivo aspirin induced ulcer and pylorus ligation assays. Gastric ulcers induced in Swiss albino rat...

The healing of gastric ulcer is a complicated process that involves the proliferation of epithelial and endothelial cells and the concerted actions of a wide range of growth factors. Prostaglandins play an important role in ulcer healing. Expression of cyclooxygenase-2 (COX-2) is markedly upregulated around the margins of gastric ulcers and its inhibition leads to a delay of ulcer healing. Seve...

OBJECTIVE This paper describes an educational model for increasing and retaining the knowledge of pressure ulcer prevention and management in veterans with spinal cord injury (SCI) or multiple sclerosis (MS) who have had surgical repair of a pressure ulcer. It also describes the correlates of pressure ulcer knowledge at admission and discharge. METHODS Before pressure ulcer surgery, 41 male v...

background dyspepsia is a common symptom with an extensive differential diagnosis and a heterogeneous pathophysiology. many studies have reported that dyspeptic symptoms are associated with ingestion of some foods. current treatments for functional dyspepsia have generally ignored the potential role of diet. method this cross-sectional study was done at the gastroenterology department of shahid...

Hereditary predisposition is one of the aetiopathogenetic factors in development gastric ulcer and duodenal ulcer. The analysis literature materials allows us to identify a number candidate genes that play role formation peptic ulcer: PSCA, ABO, IL1β, IL1RN, TNFα, HSP70-1, GSR, TLR4, TLR2, TLR9, MMP-1, MMP-3, MMP- 9, TIMP-3, PGC, MIF, MPO, COX-1. Considering most studies were carried out abroad...