Mannheimia haemolytica, Trueperella pyogenes y Pasteurella multocida son bacterias comensales de las vías respiratorias superiores los rumiantes. Sin embargo, cuando existen factores predisponentes pueden desencadenar enfermedades o incluso ocasionar la muerte. El objetivo este estudio fue determinar causas morbilidad mortalidad en terneros corderos 4 establecimientos ubicados Provincia Corrien...

The correlations between the bacteriologic agent of lamb pneumonia and its pathologic characters were investigated in this study. Pneumonia was detected in 262 (35.41%) of 740 diseased or dead lambs. Pathogenic bacteria were isolated in 114 cases (14.96% of all lamb deaths and 43.51% of all pneumonias). Lung lesions were histopathologically described as acute-catarrhal (17.56%), catarrhal-purul...

The leukotoxin of Mannheimia haemolytica is an important virulence factor that contributes to much of the pathology observed in the lungs of animals with bovine shipping fever pneumonia. We believe that identification of factors that regulate leukotoxin expression may provide insight into M. haemolytica pathogenicity. The DNA sequence upstream of the leukotoxin operon is divergently shared by P...

OBJECTIVES The aim of this study was to identify and analyse the first integrative and conjugative element (ICE) from Mannheimia haemolytica, the major bacterial component of the bovine respiratory disease (BRD) complex. METHODS The novel ICEMh1 was discovered in the whole-genome sequence of M. haemolytica 42548 by sequence analysis and comparative genomics. Transfer of ICEMh1 was confirmed b...

A 16-kbp DNA region that contains genes involved in the biosynthesis of the capsule of Mannheimia (Pasteurella) haemolytica A1 has been characterized. The gene cluster can be divided into three regions like those of the typical group II capsule biosynthetic clusters in gram-negative bacteria. Region 1 contains four genes (wzt, wzm, wzf, and wza) which code for an ATP-binding cassette transport ...

The expression of Mannheimia haemolytica A1 genes during in vivo growth was examined by reverse transcriptase-polymerase chain reaction (RT-PCR) using total RNA extracted directly from M. haemolytica A1 recovered from pneumonic lungs of cattle. Primers specific for three groups of genes were used. Group 1 includes virulence-related genes: lktC, tbpB, ahs, nmaA, gs60 and gcp. Group 2 includes ge...

BACKGROUND Pasteurella multocida, Mannheimia haemolytica, Histophilus somni and Trueperella pyogenes are four bacterial agents commonly associated with bovine respiratory disease (BRD). In this study a bacterial multiplex real-time PCR (the RespoCheck PCR) was evaluated for the detection in bronchoalveolar lavage fluid (BALF) of these four bacterial agents. RESULTS The analytical sensitivity ...

83 gram-negative bacterial pathogens, resulting in increased drug potency. Tulathromycin has shown high efficacy against the common bacterial causes of respiratory disease in cattle and swine: It is rapidly released from the injection site, promoting early achievement of inhibitory concentrations in lung tissue. Furthermore, extensive tissue penetration and slow release from tissue provide exte...

Mastitis is considered one of the most important diseases of domestic animals, caused by several etiologic agents. Transmission of the microorganisms primarily occurs by ascendant via in canal of teats, usually involving agents from animals and environmental origin and from milking process (Anderson et al., 2005). Staphylococcus aureus is recognized as the most common causal agent of goat masti...