Submit Manuscript | http://medcraveonline.com Abbreviations: LCT: Lambda-Cyhalothrin; LD: Lethal Dose; NOAEL: No-Observed-Adverse-Effect Level; Con A: Concanavalin A; SRBCs: Sheep Red Blood Cells; WBCs: White Blood Cells; Ig: Immunoglobulin; HA: Hemagglutination; QHS: Quantitative Hemolysis of SRBCs; FCS: Fetal Calf Serum; DTH: Delayed-type of Hypersensitivity Response; BMCs: Blood Mononuclear ...

The study on the antioxidant and hypolipidemic effect of pollen extracts (Cernitins) was conducted in male mongrel rabbits and Wistar rats. The animals were fed a high-fat diet (HFD) composed of cholesterol, coconut oil and cholic acid, and received pollen extracts (Cernitins) orally (the rabbits over a period of 12 weeks and the rats over a period of 2 weeks). The levels of malondialdehyde (MD...

Oxidative stress contributes to genomic instability in chronic lymphocytic leukemia (CLL), but its relationship with the acquisition of specific chromosomal abnormalities is unknown. We recruited 55 untreated CLL patients and assessed 8-oxo-2'-deoxyguanosine (8-oxo-dG), glutathione, and malondialdehyde (MDA) levels, and we compared them among the cytogenetic subgroups established using fluoresc...

Lead (Pb) is known to negatively affect glutathione (GSH) metabolism in the lens. The present study examined the effects of Captopril, Taurine, and alpha-Lipoic acid on the Pb-induced GSH depletion and lipid peroxide increase in the lenticular system. Captopril administration returned the GSH, cysteine (CYS), and malondialdehyde (MDA) levels to near normal. Following Taurine administration the ...

Drinking alcohol and smoking cigarettes results in the formation of reactive aldehydes in the lung, which are capable of forming adducts with several proteins and DNA. Acetaldehyde and malondialdehyde are the major aldehydes generated in high levels in the lung of subjects with alcohol use disorder who smoke cigarettes. In addition to the above aldehydes, several other aldehydes like 4-hydroxyn...

Background: The present study aims to examine the pharmacotherapy effects of citicoline in patients suffering traumatic brain injury with DAI and GCS less than or equal to 8 diagnosis. The treatment efficacy of citicoline was assessed by the malondialdehyde (MDA) levels in plasma as a marker of oxidative stress and GCS clinical assessment of patients. Furthermore, because of the relation betwee...

Is Malondialdehyde a Putative Uremic Toxin? B.K. Kishore B.K. Kishore, MD, BCHM 75.39 ICP/UCL, avenue Hippocrate 75, B-1200 Bruxelles (Belgium) Dear Sir, References Various studies have demonstrated that the lipid per-oxidation (LP) status of chronic renal failure (CRF) patients is significantly increased, irrespective of the dialysis treatment [1–3]. While the actual cause for this increased L...

Oxygen free radicals have been implicated as mediators of tissue damage in patients with rheumatoid arthritis. The aim of our study was to assess the lipid peroxide products and antioxidant status in rheumatoid arthritis patients (RA). The study involved determination of two plasma lipid peroxide products, malondialdehyde (MDA) and conjugated dienes (CD), two plasma antioxidant vitamins (C and ...

The aim of the study was to determine toxic effect and dynamics oxidative stress caused by mercury chloride (HgCl2) in rainbow trout (Oncorhynchus mykiss) weighing 59.43 ± 7.21 g.For this purpose, a total 40 fish 4 groups, 10 each group (n = 10), were exposed 25% 50% (137.75 μg/L 275 μg/L) LD50 for 2 7 days. To oxidative/nitrosative stress, Peroxynitrite (ONOOˉ mmol/L), Total Oxidant Level (TOS...

OBJECTIVES Reactive oxygen species (ROS) induced lipid peroxidation is associated with sperm function. Malondialdehyde (MDA) concentration and glutathione peroxidase (GPx) activity represent the lipid peroxidation and spermicidal antioxidant, respectively. We aimed to evaluate the relationship of MDA and GPx levels with sperm parameters. PATIENTS AND METHODS Specimens were divided into two gr...