background : major depressive disorder is one of the most widespread psychological problems in the world. the feelings of a person who is affected by this condition is boring. this article aimed to shed light on the experiences of women with major depressive disorder. methods : a qualitative approach with thematic analysis design has been used to describe the studied phenomenon as experienced b...

This study was undertaken to investigate psychiatric comorbidity in male and female adolescents with conduct disorder diagnoses. Twenty-five hospitalized adolescents (11 females, 14 males) with conduct disorder were evaluated using structured diagnostic interviews for Axis I and personality disorders. The most common Axis I comorbid diagnoses were: depressive disorders (major depression and/or ...

OBJECTIVE The principal aims of this study were to examine the prevalence rate, clinical characteristics, and related factors of postpartum obsessive-compulsive disorder (OCD). METHOD The subjects were a nonclinical sample of 400 postpartum women. They were interviewed from the 2nd up to the 26th week after birth. The Mini International Neuropsychiatric Interview was used for diagnosis of OCD...

Abstract Deep brain stimulation (DBS) of the anterior limb internal capsule (ALIC) has shown promise as a therapy for refractory obsessive-compulsive disorder (OCD) and major depressive (MDD). DBS currently is ‘open-loop’ with parameters remaining fixed over time. In contrast, ‘closed-loop’ delivers only when biomarker target symptom state indicates it needed. One challenge to development close...

We conducted a meta-analysis of randomized trials in which the effects of treatment with antidepressant medication were compared to the effects of combined pharmacotherapy and psychotherapy in adults with a diagnosed depressive or anxiety disorder. A total of 52 studies (with 3,623 patients) met inclusion criteria, 32 on depressive disorders and 21 on anxiety disorders (one on both depressive a...

OBJECTIVE To measure the association of perfectionism with obsessive-compulsive and depressive symptoms in children and adolescents with obsessive-compulsive disorder (OCD). METHOD Sample consisted of 94 youth (44 boys, 49 girls; mean age = 13.2 y, SD = 2.5 y) with a DSM-IV diagnosis of OCD. Perfectionism beliefs were measured with both the Adaptive/Maladaptive Perfectionism Scale (AMPS) and ...

The personal, social and economic burden of post-traumatic stress disorder (PTSD) is high and therapeutic approaches are only partially effective. Therefore, there is an urgent need to understand the cellular and molecular alterations in PTSD brains in order to design more effective treatment strategies. Although brain imaging strategies have considerably improved our understanding of PTSD, the...

objective: major depression is a mood disorder that causes changes in physical activity, appetite, sleep and weight. regarding the role of zinc in the pathology of depression, the present study was aimed to investigate the effects of zinc supplementation in the treatment of this disease. methods: this study was a double-blind randomized clinical trial. forty four patients with major depression ...

conclusions serum t4 and tsh levels in depressive patients were found to be significantly higher than those of the control group, indicating the association between serum t4 and tsh levels and depression in the subjects in 2010 - 2011 in hamedan, northwestern iran. objectives in this study, the serum levels of t3, t4, and tsh in patients with major depressive disorder have been compared to the ...