BACKGROUND Autistic personality traits (APT) and schizotypal personality traits (SPT) are associated with depression. However, mediating factors within these relationships have not yet been explored. Thus, the focus of the current study was to examine the effects of childhood neglect on the relationship between APT/SPT and depression. METHODS This cross-sectional study was conducted on first-...

Central pain syndrome (CPS) is a debilitating condition that affects a large number of patients with a primary lesion or dysfunction in the CNS, most commonly due to spinal cord injury, stroke, and multiple sclerosis lesions. The pathophysiological processes underlying the development and maintenance of CPS are poorly understood. We have recently shown, in an animal model of CPS, that neurons i...

BACKGROUND The correct perioperative management of antiplatelet therapy (APT) in patients undergoing non-cardiac surgery (NCS) is often debated by clinicians. American College of Cardiology (ACC) and American Heart Association (AHA) guidelines recommend postponing elective NCS at least 3 months after stent implantation. Regardless of the timing of surgery, ACC/AHA guidelines recommend continuin...

BACKGROUND AND PURPOSE Many patients receiving thrombolysis for acute ischemic stroke are on prior antiplatelet therapy (APT), which may increase symptomatic intracerebral hemorrhage risk. In a prespecified subgroup analysis, we report comparative effects of different doses of intravenous alteplase according to prior APT use among participants of the international multicenter ENCHANTED study (E...

Abstract Background Ti 3 C 2 is a type of transition metal carbides and nitrides (MXenes) with high light-to-heat conversion efficiency property, which has been widely used in cancer treatment recently. In fact, active targeting delivery MXenes nanomaterials molecule could enhance the therapeutic efficacy. However, targeted therapy not further studied past. Aptamers (Apt) excellent affinity spe...

Establishing the biological profile of an unknown skeleton is one forensic anthropologist main tasks; sex them. In sexing skulls, specific standard assessment designed for each population can improve accuracy rate due to its population-specific traits. This study aims describe sexual dimorphism in contemporary Javanese crania while employing metric methods. The measurements 50 male and 37 femal...

BACKGROUND Atopic dermatitis is commonly associated with food allergy. In addition to skin prick tests (SPTs) and measurements of specific IgE levels, the atopy patch test (APT) has recently been introduced into the diagnostic procedure for food allergy. OBJECTIVE Our aim was to evaluate whether a combination of allergologic tests could improve the prognostic value of the individual tests for...

Chemical exchange saturation transfer (CEST) provides an indirect means to detect exchangeable protons within tissues through their effects on the water signal. Previous studies have suggested that amide proton transfer (APT) imaging, a specific form of CEST, detects endogenous amide protons with a resonance frequency offset 3.5 ppm downfield from water, and thus may be sensitive to variations ...

Pictorial metaphor is a popular way of expression in creative advertising. It attributes certain desirable quality to the advertised product. We adopt a general twostage computational approach in order to generate apt metaphor ideas for pictorial advertisements. The first stage looks for concepts which have high imageability and the selling premise as one of their prototypical properties. The s...

This paper analyzes public goods whose benefits cross countries’ borders and generations. Once provided, transnational intergenerational public goods (TIPGs) are assets that generate benefits for subsequent generations. For treaties involving TIPGs, a coalition of rich developed countries are apt to shoulder more of the provision burden then a coalition of poor developing countries. This burden...