We report here the complete variable (V) region sequence of a nonfunctionally rearranged Vk gene from the BAIB/c derived myeloma cell line P3X63-Ag 8.653, which is the most ouinon fusion partner used in hybridoma technology. Corresponding cDtft clones were isolated from 2 independent cDNA libraries to autoantibody-secreting hybridoma lines in which they occured at a frequency of about 5% of fun...

Twenty-eight new substituted N-phenyl ureidobenzenesulfonate (PUB-SO) and 18 N-phenylureidobenzenesulfonamide (PUB-SA) derivatives were prepared. Several PUB-SOs exhibited antiproliferative activity at the micromolar level against the HT-29, M21, and MCF-7 cell lines and blocked cell cycle progression in S-phase similarly to cisplatin. In addition, PUB-SOs induced histone H2AX (γH2AX) phosphory...

for some constant C. We may want to colour every vertex uniformly at random. Then we will get m21−k many monochromatic edges in expectation. An improvement upon the basic method can be obtained by randomly recolouring all monochromatic edges after the first randomization. In a 1978 proof, Beck used this argument to show that m(k) ≥ Ω(k2). In 2000, Radhakrishnan and Srinivasan improved it to m(k...

The paper shows how excessive reporting, called “crying wolf”, can dilute the information value of reports. Excessive reporting is investigated by undertaking the first formal analysis of money laundering enforcement. Banks monitor transactions and report suspicious activity to government agencies, which use these reports to identify investigation targets. Banks face fines should they fail to r...

Academics and practitioners have long recognized the importance of a firm’s industry membership in explaining its financial performance. Yet, contrary to conventional wisdom, recent research shows that industry-specific profitability forecasting models are not better than economy-wide models. This paper re-examines the incremental advantage of industry-specific models. We find considerable indu...

As a contribution to the hypothesis of mixing of three active neutrinos with, at least, one sterile neutrino, we report on a simple 4× 4 texture whose 3× 3 part arises from the popular bimaximal texture for three active neutrinos νe , νμ , ντ , where c12 = 1/ √ 2 = s12, c23 = 1/ √ 2 = s23 and s13 = 0. Such a 3 × 3 bimaximal texture is perturbed through a rotation in the 14 plane, where ν4 is th...

In a previous paper, we gave a new theoretical framework in which three neutrino mixing in matter are discussed. Rigorous analytical solutions are obtained. In present paper an approximate method is developed for studying three flavor neutrino oscillations in matter in the new framework. Using condition of ∆m21 ≪ ∆m22, decoupled resonances, which is discovered by Kuo et al. previously, are obta...

The physics implications of the just published salt phase data from the SNO experiment are examined. The effect of these data on the allowed ranges of the solar neutrino oscillation parameters, ∆m21 and sin 2 θ12, are studied in the cases of twoand threeneutrino mixing. In the latter case we derive an upper limit on the angle θ13. Constraints on the solar νe transitions into a mixture of active...

It is shown that the hybrid MSW + VO solution of the solar neutrino problem, according to which the solar νe undergo matter-enhanced transitions into νμ,τ in the Sun followed by long wave length (∼ 1.5×108 km) νe ↔ νμ,τ oscillations in vacuum between the Sun and the Earth, can occur naturally in string-motivated grand unified theories. We consider the supersymmetric version of a string-type SU(...