For more than a decade, phage displayed combinatorial antibody libraries have been used to generate and select a wide variety of antibodies. We previously reported that the phage coat proteins pVII and pIX could be used to display the heterodimeric structure of the antibody Fv region. Herein, aspects of this technology were invoked and extended to construct a large, human single-chain Fv (scFv)...

Little is known about the genetic program that generates synaptic specificity. Here we show that a putative transcription factor, Teyrha-Meyhra (Tey), controls target specificity, in part by repressing the expression of a repulsive cue, Toll. We focused on two neighboring muscles, M12 and M13, which are innervated by distinct motoneurons in Drosophila. We found that Toll, which encodes a transm...

Bacterial extracellular peptidases are important for bacterial nutrition and organic nitrogen degradation in the ocean. While many peptidases of the M13 family from terrestrial animals and bacteria are studied, there has been no report on M13 peptidases from marine bacteria. Here, we characterized an M13 peptidase, PepS, from the deep-sea sedimentary strain Shewanella sp. E525-6, and investigat...

We present preliminary results from HST/WFPC2 observations of the central regions of the of the Galactic globular clusters M13 & M3. The clusters are almost identical in most respects including chemical composition, but there are dramatic differences in both the horizontal branch (HB) and blue straggler (BSS) populations. The M13 HB has a long blue tail extending 4.5 mag in V, reaching well bel...

The Wide Field Camera 3 (WFC3) is fitted with three grisms for slitless spectroscopy. In the UVIS channel there is one grism, G280, for the near-UV to visible range (200 400nm; 1.4nm/pix). The IR channel has two grisms: G102 for the shorter (800-1150nm; 2.45nm/pix) and G141 for the longer (1100-1700nm; 4.65nm/pix) NIR wavelengths. Using SMOV and Cycle 17 calibration data taken on WR stars, plan...

We report here the construction of a bacteriophage M13-templated supramolecular nanosystem, i.e. M13-β-CD/Ada-FITC/Ada-RhB, which can be used as effective ratiometric fluorescent sensors for intracellular sensing.

Analisou-se o efeito da percepção do mobile banking na satisfação com sistema PIX para um grupo de jovens adultos, os estudantes universitários. Foram utilizados método survey, estatísticas descritivas, análise fatorial confirmatória e modelagem equações estruturais. validados oito construtos primeira ordem compor a Percepção (Mindfulness, Utilidade percebida, Facilidade uso, Influência social,...