Background: Many plants possess therapeutic properties against infectious and non-infectious diseases, including cancer inflammatory diseases. Plants may have immunomodulatory properties, too. In this study, we evaluated the effects toxic of ethanolic extract from Lamiaceae family on macrophage, lymphocyte, B Cell Leukemia (BCL-1) in vitro. Materials Methods: Plant samples were purchased, their...

Background and Aims: Rubella is predominantly a childhood disease that is endemic throughout the world and when rubella outbreaks occur, they are accompanied by birth defects following congenital rubella syndrome. Immunity to rubella virus as a teratogenic agent has an important role for prevention of these serious congenital defects. Lymphocyte proliferation assay is a way for investigation of...

The autologous mixed lymphocyte reaction is impaired in patients with systemic lupus erythematosus. This is because nonthymus-derived (T)-lymphocyte preparations from such patients do not stimulate autologous T-lymphocyte proliferation normally. This defect may explain the impaired generation of suppressor activity in systemic lupus erythematosus and thereby the occurrence of autoantibodies in ...

BACKGROUND The life expectancy of patients with cystic fibrosis (CF) is largely dependent on the pulmonary disease severity and progress. Malnutrition may be an important complicating factor in active and chronic lung disease. AIMS The focus of this study was to investigate several inflammatory markers in pancreatic-insufficient CF patients with different enzyme treatment regimens. METHODS ...

With new techniques 1 9 bone marrow transplant (BMT) recipients were monitored for lymphocyte proliferation and specific lgG production in vitro by cytomegalovirus (CMV) antigen in solid phase. Twelve patients got a reactivated CMV infection as defined by virus isolation or serum lgG conversion. Lymphocyte proliferation and in vitro lgG production responses were significantly stronger in these ...

four known flavonoids: quercetin 3-o-β-d-rutinoside (q3rut), myricetin 3-o-β-d-galactopyranoside (m3gal), quercetin 3-o-β-d-galactopyranoside (q3gal) and quercetin 3-o-β-d-glucopyranoside (q3glc), for the first time were isolated from aerial parts of euphorbia microsciadia. the chemical structure of them was elucidated on the basis of 1 and 2 d-nmr spectra and different spectroscopic techniques...

Abstract Cancer and highly proliferating normal cells have high demand for energy but paradoxically switch production from the efficient mitochondrial respiration to low cytosolic glycolysis. This phenomenon is known as Warburg effect, reason which not fully understood. study found that intracellular pH (pHi) induced apoptosis, whereas pHi enhanced proliferation, of lymphocytes. In tumor cells,...

Our previous study has showed that restraint stress inhibits T cell proliferation. Kv1.3 plays a key role in the lymphocyte activation process. Here, we investigate the effects of restraint stress on murine splenic T and B cell proliferation and the role of Kv1.3 in the process. 3H-TdR incorporation is used to determine changes in splenocyte proliferation stimulated by Con A or LPS between cont...

Objective(s): New generation of allergy vaccines is capable of promoting the development of protective IgG and blocking the functionality of allergen-specific IgE. We incorporated universal and powerful T-cell epitopes from tetanus and diphtheria toxoids (TD epitope) into recombinant Che a 2, the well-known allergic profilin of Chenopodium album, to determine its immun...

INTRODUCTION Canova (CA) is a homeopathic medication with immunomodulatory properties, recommended for patients with a depressed immune system. CA has been reported to increase in leukocyte numbers, cellular differentiation and reduction in tumor size. AIM AND METHOD Since CA may stimulate lymphocyte differentiation, proliferation, and/or survival, the aim of the present study was to compare ...