Journal:
:iranian journal of pharmaceutical research
0
ramin miri medicinal and natural products chemistry research center, shiraz university of medical sciences. shiraz, iran.
pharmaceutical sciences research center, tehran university of medical sciences. tehran, 14174, iran
omidreza firuzi medicinal and natural products chemistry research center, shiraz university of medical sciences. shiraz, iran.
payam peymani medicinal and natural products chemistry research center, shiraz university of medical sciences. shiraz, iran.
zohreh nazarian pharmaceutical sciences research center, tehran university of medical sciences. tehran, 14174, iran.
department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
abbas shafiee pharmaceutical sciences research center, tehran university of medical sciences. tehran, 14174, iran.
department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran.
dna intercalators belong to aromatic heterocyclic compounds interacting reversibly with dna. these compounds have been used extremely as cytotoxic agents against cancer. in this study, the synthesis and biological activity of some novel derivatives of cyclopenta [b] quinoline-1, 8-dione as new intercalating agent were investigated. twenty novel derivatives of cyclopenta [b] quinoline-1, 8-dione...