Objective: Inflammation along with oxidative stress has an important role in the pathophysiology of unstable angina which leads to acute myocardial infarction, arrhythmias and eventually heart failure. Curcumin has anti-inflammatory and anti-oxidant effects and thereby, it may reduce cardiovascular complications. This randomized controlled trial aimed to investigate the effects of curcumin on t...

From CERMAV-CNRS (affiliated to Université Joseph Fourier and ICMG, 38041 Grenoble, France, Albert-Ludwigs-University Freiburg, Institute of Biology II and BIOSS Centre for Biological Signalling Studies, 79104 Freiburg, Germany, # Institut Curie, Centre de Recherche, Traffic, Signaling and Delivery group, CNRS UMR 144, 75248 Paris, France, Inserm, U892, University of Nantes, IRT UN, 44007 Nante...

BACKGROUND Angina is common both before and after myocardial infarction (MI). Whether the change in angina status within the first 30 days after MI is associated with subsequent readmission and angina persistence is unknown. METHODS AND RESULTS We studied 2915 MI patients enrolled at 24 hospitals in the Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction...

We investigated the prognostic significance of new-onset angina in patients in whom coronary anatomic characteristics were known. New onset angina was defined as angina of less than 3 months duration. Consecutive patients (n = 1727) with significant coronary artery disease (diagnosed at cardiac catheterization) and who had not had a prior myocardial infarction or congestive heart failure were s...

background and purpose: regarding usefulness of revascularization versus optimal medical therapy in patients with stable angina pectoris, data are challenging. the aim of this 12-month follow-up study was to compare the survival benefit associated with revascularization versus optimal medical therapy on the patients with stable angina pectoris. materials and methods: a prospective clinical stud...

AIMS This article reports a randomized controlled trial of lay-facilitated angina management (registered trial acronym: LAMP). BACKGROUND Previously, a nurse-facilitated angina programme was shown to reduce angina while increasing physical activity, however most people with angina do not receive a cardiac rehabilitation or self-management programme. Lay people are increasingly being trained t...

The effect of smoking five non-nicotine cigarettes and of breathing carbon monoxide on exercise-induced angina was evaluated in 12 patients with angina. Smoking increased venous carboxyhemoglobin from 1.71 to 5.35%, decreased exercise duration until angina 45%, increased ischemic ST-segment depression at angina from 1.33 to 1.52 mm, and decreased systolic blood pressure times heart rate at angi...

OBJECTIVE To assess whether neopterin concentrations in women with unstable angina differ from those in women with chronic stable angina. DESIGN Prospective cohort study. SETTING University hospital in south west London. PATIENTS 114 consecutive women with angina were studied: 82 had chronic stable angina (typical exertional chest pain, positive exercise ECG testing, and/or abnormal myoca...