نتایج جستجو برای: lsd

تعداد نتایج: 3689  

Journal: :Psychological medicine 2016
R L Carhart-Harris M Kaelen M Bolstridge T M Williams L T Williams R Underwood A Feilding D J Nutt

BACKGROUND Lysergic acid diethylamide (LSD) is a potent serotonergic hallucinogen or psychedelic that modulates consciousness in a marked and novel way. This study sought to examine the acute and mid-term psychological effects of LSD in a controlled study. METHOD A total of 20 healthy volunteers participated in this within-subjects study. Participants received LSD (75 µg, intravenously) on on...

Journal: :Revue scientifique et technique 2011
S S A Sharawi I H A Abd El-Rahim

An outbreak of lumpy skin disease (LSD) occurred among cattle and water buffaloes in Egypt in 2006. Polymerase chain reaction (PCR) and the agar gel precipitation test (AGPT) were compared. Eight of ten (80%) tissue specimens from diseased cattle were positive with AGPT while 100% were positive with PCR. Of ten tissue specimens from diseased water buffaloes, 70% were positive with AGPT while 10...

Journal: :Pharmacology, biochemistry, and behavior 1992
P A Palumbo J C Winter

The stimulus effects of ibogaine were compared with those of yohimbine, an alpha 2-adrenoceptor antagonist, 2,5-dimethoxy-4-methylamphetamine (DOM), a 5-hydroxytryptamine2 (5-HT2) agonist, and lysergic acid diethylamide (LSD), a nonspecific 5-HT agonist. Rats were trained with either yohimbine (6 mg/kg), DOM (0.6 mg/kg), or LSD (0.1 mg/kg) vs. no treatment in a two-lever discrimination task. Te...

Journal: :Brain research 1977
B L Jacobs M E Trulson W C Stern

In the course of examining the complete dose-response relationship for the behavioral effects of LSD in the cat, we discovered that, in addition to large increases in investigatory and hallucinatory-like responses, two behaviors, not previously reported, are emitted with a high probability under LSD. Beginning from a baseline of essentially zero in saline-treated animals, limb flicks and aborti...

Journal: :Canadian journal of psychiatry. Revue canadienne de psychiatrie 2005
Erika Dyck

In the popular mind, d-lysergic acid diethylamide (LSD) research in psychiatry has long been associated with the CIA-funded experiments conducted by Ewen Cameron at the Allen Memorial Institute in Montreal, Quebec. Despite this reputation, a host of medical researchers in the post World War II era explored LSD for its potential therapeutic value. Some of the most widespread trials in the Wester...

Journal: :Molecular pharmacology 1985
A B Norman G Battaglia I Creese

In the presence of a 30 nM prazosin mask, [3H]-2-(2,6-dimethoxyphenoxyethyl) aminomethyl-1,4-benzodioxane ([3H]WB4101) can selectively label 5-HT1 serotonin receptors. Serotonin exhibits high affinity (Ki = 2.5 nM) and monophasic competition for [3H] WB4101 binding in cerebral cortex. Furthermore, we have found a significant correlation (r = 0.96) between the affinities of a number of serotoner...

Journal: :Journal of psychopharmacology 2015
Peter Gasser Katharina Kirchner Torsten Passie

OBJECTIVE A recently published study showed the safety and efficacy of LSD-assisted psychotherapy in patients with anxiety associated with life-threatening diseases. Participants of this study were included in a prospective follow-up. METHOD 12 months after finishing LSD psychotherapy, 10 participants were tested for anxiety (STAI) and participated in a semi-structured interview. A Qualitativ...

Journal: :EURASIP J. Adv. Sig. Proc. 2004
Jianhua Liu Jian Li

We present a hybrid soft detector that has a good performance/complexity trade-off for a multiple-input multiple-output (MIMO) wireless communication system with known channel information. The new soft detector combines the merits of a simple unstructured least-squares (LS)-based soft detector and a list sphere decoder (LSD)-based soft detector for data bit detection. The former is computationa...

Journal: :ANZ journal of surgery 2013
Xiao-Dong Chen Fu-Qian He Lie Yang Yong-Yang Yu Zong-Guang Zhou

BACKGROUND Open splenectomy and devascularization are effective treatments for cirrhotic patients with severe thrombocytopenia and variceal bleeding. However, it remains controversial whether laparoscopic splenectomy (LS) and devascularization (LSD) can be indicated and beneficial in these patients. OBJECTIVES A systematic review of the efficacy and safety of LS and LSD for patients with live...

2016
Toru TSUJIMURA Masaki HAYASHIDA

We used the quantitative receptor autoradiographic method with a radioligand of [ 125I ]lysergic acid diethylamide ([125I]LSD) to quantitate platelet serotonin (5-HT)2A receptors in affective disorders. Specific binding of [125I]LSD to human platelet pellet sections was saturable, and of high affinity and single. Both ketanserin and spiperone, 5-HT2A selective ligands, inhibited [125I]LSD bindi...

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