Fourteen patients with critical aortic stenosis (valve area 0.4 cm2/m2), a history of advanced congestive heart failure, left ventricular ejection fraction less than 0.45 (mean 0.28 d 0.03) and no other valvular lesions or obstructive coronary artery disease were studied to assess prognosis with aortic valve replacement. Eleven of 14 (79%) survived surgery; 10 of these 11 showed major clinical ...

Low gradient aortic stenosis can be caused by critical aortic stenosis causing left ventricular impairment or by more moderate aortic stenosis coexisting with another cause of left ventricular impairment. The main challenges are to differentiate these two states and then to determine whether the left ventricle is likely to recover after aortic valve surgery. Exhaustive echocardiography is neces...

Multiple measurements of left ventricular volumes, ejection fractions, and circulatory pressures were made under conditions of varied outflow resistance in five intact anesthetized dogs by using a biplane videoangiographic recording system which displays simultaneously two roentgen images on the same television screen, records the images on video tape, and requires low radiation levels and smal...

catheterization study. Circulation 2013;128:S235–S242. 18. Dumesnil JG, Pibarot P. Letter by Dumesnil and Pibarot regarding article, ‘Outcome of patients with low-gradient ‘severe’ aortic stenosis and preserved ejection fraction’. Circulation 2011;124:e360. 19. Cueff C, Serfaty JM, Cimadevilla C, Laissy JP, Himbert D, Tubach F, Duval X, Iung B, Enriquez-Sarano M, Vahanian A, Messika-Zeitoun D. ...

Ventricular function during exercise in patients with mitral stenosis has not been widely studied. Accordingly, 20 patients with isolated mitral stenosis were assessed during supine, symptom-limited equilibrium radionuclide ventriculographic studies. All patients had a normal left ventricular (LV) ejection fraction at rest (greater than or equal to 50 percent), and all were in sinus rhythm. Lef...

Current prevention of major adverse cardiovascular events (MACE) after acute coronary syndromes (ACS) is based on aggressive medical therapy, and guideline-driven treatment of traditional coronary risk factors. These include achieving low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood pressure, and glycosylated hemoglobin target levels, smoking cessation, and physi...

OBJECTIVE To evaluate the role of plasma neurohormones in the diagnosis of asymptomatic or minimally symptomatic right ventricular dysfunction. SETTING Tertiary cardiovascular referral centre. METHODS Plasma brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) concentrations were measured in 21 asymptomatic or minimally symptomatic patients with chronic right ventricular pre...

background: the aim of this study was to investigate the correlation between the cardiac and hepatic iron-overload as assessed by magnetic resonance imaging t2 star (mrit 2 -star) technique and serum ferritin level in patients with thalassemia major. methods: in this cross-sectional study we evaluated 170 patients in sayed shohada hospital in isfahan in the year of 2009, cardiac and hepatic iro...