BACKGROUND In 1999, a World Health Organization (WHO) committee published histologic criteria for distinct thymoma entities (labeled as Type A, AB, B1, B2, B3 thymomas) and for the heterogeneous group of thymic carcinomas, collectively called Type C thymomas. Whether WHO-defined histologic thymoma subtypes are of independent prognostic relevance has yet to be proved. METHODS Two hundred thymo...

background and objectives: survival models are statistical technique to estimate or predict the overall time up to specific events. prediction is important in medical science and the accuracy of prediction is determined by a measurement, generally based on loss functions, called prediction error. the aim of this study is using parametric models to determine the factors influencing predicted sur...

A rank-select index for a sequence B = (b1, . . . , bn) of n bits, where n ∈ N = {1, 2, . . .}, is a data structure that, if provided with an operation to access Θ(log n) arbitrary consecutive bits of B in constant time (thus B is stored outside of the data structure), can compute rankB(j) = ∑j i=1 bi for given j ∈ {0, . . . , n} and selectB(k) = min{j ∈ N | rankB(j) ≥ k} for given k ∈ {1, . . ...

Survival curves for each group gives comparison at some arbitrary point(s) but it does not provide a comparison of the total survival experience of two groups. So some Non-parametric methods like log rank test, Cox-Mantel test are popular methods used for comparing the survival distribution and also these methods takes whole follow-up period. In this paper non-parametric methods are used for da...

This review introduces methods of analyzing data arising from studies where the response variable is the length of time taken to reach a certain end-point, often death. The Kaplan-Meier methods, log rank test and Cox's proportional hazards model are described.

METHODS: We analyzed data from our institution’s prospectively collected National Cancer Institute-Designated Comprehensive Cancer Center Tumor Registry. We compared mastectomy-only patients to post-mastectomy breast reconstruction patients. We built Kaplan-Meier curves for both groups and compared unadjusted survival statistics using Log-rank test. We then used Cox Proportional Hazards to adju...

Objective: The aim of this study is to determine the outcome of trastuzumab therapy for 6 or 12 months in patients with HER2 positive operable breast cancer who followed the national health insurance system in Indonesia. Methods: Data were extracted from medical records of Dr. M Djamil General Hospital Padang and Dharmais Cancer Hospital/ National Cancer Center Jakarta for post-operative breast...

BACKGROUND We prospectively investigated lepirudin for further parenteral anticoagulation in patients with heparin-induced thrombocytopenia (HIT). METHODS AND RESULTS Patients with confirmed HIT (n=112) received lepirudin according to need for 2 to 10 days (longer if necessary): A1, treatment: 0.4 mg/kg IV bolus, followed by 0.15 mg. kg(-1). h(-1) intravenous infusion, n=65; A2, treatment in ...