How does the brain determine the position of moving objects? It turns out to be rather complex to answer this question when we realize that the brain has to solve the motion correspondence problem in two kinds of reference frames: Retinotopic and non-retinotopic ones. We show that visual objects are mislocalized along a non-retinotopic motion direction. Observers viewed two successive movie fra...

HYPOTHESIS Colonoscopic localization of colorectal carcinoma is frequently inaccurate and unreliable. DESIGN Consecutive case series. SETTING Tertiary care teaching hospital. PATIENTS Three hundred fourteen consecutive patients undergoing surgical resection for colorectal cancer from January 1, 2000, to December 31, 2003. INTERVENTION Surgical resection for colorectal cancer. MAIN OUT...

B-cell receptors form ordered clusters to recruit kinases and exclude phosphatases.

By leveraging large clusters of commodity hardware, the Cloud offers great opportunities to optimize the operative costs of software systems, but impacts significantly on the reliability of software applications. The lack of control of applications over Cloud execution environments largely limits the applicability of state-of-the-art approaches that address reliability issues by relying on heav...

Non-viral gene delivery is plagued by low transfection levels compared to viral delivery. The nuclear envelope presents a significant obstacle for non-viral vectors. A peptide-based nuclear localizing sequence has been incorporated into non-viral vectors to traverse the nuclear envelope. Here, we selected a photo-chemical method for covalently labeling the peptide onto plasmid DNA. The hypothes...