This study has examined endometrial tissue in 14 normal women prior to insertion of a levonorgestrel-releasing intrauterine system (LNG-IUS) and thereafter longitudinally for up to 12 months post-insertion. The specific endpoints examined by immunohistochemistry were progesterone receptor (PR) subtypes A + B, oestrogen receptor (ER) and prostaglandin dehydrogenase (PGDH). Two antiprogesterone r...

OBJECTIVE To test the hypothesis that oral desogestrel (DSG) plus testosterone would uniformly and rapidly suppress sperm concentrations in young men as effectively as levonorgestrel (LNG) plus testosterone and cause less high-density lipoprotein (HDL) suppression and weight gain. DESIGN Single-blind, randomized trial. SETTING VA Puget Sound and University of Washington, Seattle, Washington...

OBJECTIVE To evaluate the efficacy of levonorgestrel intrauterine systems (LNG-IUS) in obese women with AUB on anticoagulant therapy. DESIGN Prospective observational case series (Canadian Task Force Classification II-3). SETTING University affiliated teaching hospital. PATIENTS Premenopausal women on Warfarin therapy. INTERVENTIONS From January 2002 through January 2007, 10 women were ...

BACKGROUND The use of intrauterine devices as a contraceptive method has been steadily growing in developing countries. Anemia in reproductive-age women is a growing concern in those settings. STUDY DESIGN A systematic review of studies with measured hemoglobin and serum ferritin at baseline and after 1 year of use of copper intrauterine devices (IUDs) or a levonorgestrel-releasing intrauteri...

The effects of the proton pump inhibitor lansoprazole on the bioavailability of a low-dose oral contraceptive (OC), containing 0.03 mg ethinyloestradiol (EE) and 0.15 mg levonorgestrel (LNG), were investigated. Twenty-four healthy females (aged 19-35 years; weight 60.6 +/- 7.1 kg) participated in a multiple-dose, placebo-controlled, randomized two-way cross-over study. All subjects received the...

OBJECTIVE To determine an estimated incidence of uterine perforations related to the insertion of a levonorgestrel-releasing intrauterine system (LNG IUS) and to identify possible risk factors. DESIGN Retrospective, case report study. SETTING Hospitals in Limburg, the Netherlands. METHODS Gynecologists in hospitals in Limburg were asked about uterine perforations related to the insertion ...

Liquefied natural gas (LNG) is natural gas that has been transformed to liquid form for the purpose of transportation, which is mainly done by specially built LNG vessels travelling from the production site to the consumers. We describe a real-life ship routing and scheduling problem from the LNG business, with both inventory and berth capacity constraints at the liquefaction port. We propose a...

A LNG plant with MRC cycle would not work under the designed condition all the time. It is significant to know the performance of a fixed MRC plant working at changed working condition. The problem involves the problem of plant simulation, which is somewhat similar to but actually different with the process simulation which is used in the design of a LNG plant. A model of MRC plant simulation w...

the levonorgestrel-releasing intrauterine system We write to report a recent European survey of factors that motivate women to use or reject the levonorgestrel-releasing intrauterine system (LNG-IUS). The survey comprised focus group sessions to identify barriers that prevent women using the LNG-IUS and individual interviews with current users to identify their reasons for having chosen the LNG...

The international liquefied natural gas (LNG) trade is expanding rapidly. Projects are being proposed worldwide to meet the industry forecasted growth rate of 12 percent by the end of the decade. LNG train designs in the coming years appear to fall within three classes, having nominal capacities of approximately 3.5, 5.0, and 8.0 million tons per annum (MTPA). These designs may coexist in the c...