نتایج جستجو برای: living nematode

تعداد نتایج: 193470  

Journal: :Current Biology 2012
Andrea Choe Stephan H. von Reuss Dima Kogan Robin B. Gasser Edward G. Platzer Frank C. Schroeder Paul W. Sternberg

BACKGROUND Nematodes are among the most successful animals on earth and include important human pathogens, yet little is known about nematode pheromone systems. A group of small molecules called ascarosides has been found to mediate mate finding, aggregation, and developmental diapause in Caenorhabditis elegans, but it is unknown whether ascaroside signaling exists outside of the genus Caenorha...

Journal: :Journal of nematology 1998
Z X Chen D W Dickson

Pasteuria penetrans is a mycelial, endospore-forming, bacterial parasite that has shown great potential as a biological control agent of root-knot nematodes. Considerable progress has been made during the last 10 years in understanding its biology and importance as an agent capable of effectively suppressing root-knot nematodes in field soil. The objective of this review is to summarize the cur...

2013
Katarzyna Donskow-Łysoniewska Justyna Bien Klaudia Brodaczewska Katarzyna Krawczak Maria Doligalska

The precise mechanism of the very effective therapeutic effect of gastrointestinal nematodes on some autoimmune diseases is not clearly understood and is currently being intensively investigated. Treatment with living helminths has been initiated to reverse intestinal immune-mediated diseases in humans. However, little attention has been paid to the phenotype of nematodes in the IBD-affected gu...

Journal: :Applied and environmental microbiology 1994
A J Smigielski R J Akhurst N E Boemare

Phase variation in Xenorhabdus and Photorhabdus spp. has a significant impact on their symbiotic relationship with entomopathogenic nematodes by altering the metabolic by-products upon which the nematodes feed. The preferential retention of the phase I variant by the infective-stage nematode and its better support for nematode reproduction than phase II indicates its importance in the bacterial...

2016
Ashley N. Luck Xiaojing Yuan Denis Voronin Barton E. Slatko Iqbal Hamza Jeremy M. Foster

Nematodes lack a heme biosynthetic pathway and must acquire heme from exogenous sources. Given the indispensable role of heme, this auxotrophy may be exploited to develop drugs that interfere with heme uptake in parasites. Although multiple heme-responsive genes (HRGs) have been characterized within the free-living nematode Caenorhabditis elegans, we have undertaken the first study of heme tran...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Jun-Zhi Wei Kristina Hale Lynn Carta Edward Platzer Cynthie Wong Su-Chiung Fang Raffi V Aroian

Bacillus thuringiensis (Bt) crystal proteins are pore-forming toxins used as insecticides around the world. Previously, the extent to which these proteins might also target the invertebrate phylum Nematoda has been mostly ignored. We have expressed seven different crystal toxin proteins from two largely unstudied Bt crystal protein subfamilies. By assaying their toxicity on diverse free-living ...

Journal: :Journal of nematology 1992
B C Hyman C H Opperman

Elucidating the biochemical basis of host-parasite relationships will be instrumental in the success of biologically based control in agriculture. This challenge is an ambitious one, but several central themes emerge regarding the roles of both parasiteand host-derived molecules. These include their contribution to nematode attraction, recognition, and reproduction as well as the response of pl...

Journal: :Parasitology 2011
Gillian Stepek Gillian McCormack Andrew J Birnie Antony P Page

Nematodes represent one of the most abundant and species-rich groups of animals on the planet, with parasitic species causing chronic, debilitating infections in both livestock and humans worldwide. The prevalence and success of the nematodes is a direct consequence of the exceptionally protective properties of their cuticle. The synthesis of this cuticle is a complex multi-step process, which ...

2015
Claudia M. Wever Danielle Farrington Joseph A. Dent Clotilde K. S. Carlow

New compounds are needed to treat parasitic nematode infections in humans, livestock and plants. Small molecule anthelmintics are the primary means of nematode parasite control in animals; however, widespread resistance to the currently available drug classes means control will be impossible without the introduction of new compounds. Adverse environmental effects associated with nematocides use...

Journal: :Journal of nematology 2006
R Chevalier J M Webster

To assess the effect of an inundative release of entomopathogenic nematodes on soil organisms, population densities of soil-dwelling organisms were monitored before and after an application of an aqueous suspension of Heterorhabditis megidis to field plots in mown grassland (Exp. I) at a level of 0.38 million/m(2) and to plots (Exp. II) situated in a forested area, a grass sports field and an o...

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