BACKGROUND Donor safety and preservation of donor health after living liver donation are of paramount importance. Diarrhea has a significant influence on gastrointestinal quality of life among donors who have undergone living donor hepatectomy. Thus, we aimed to investigate predictors of diarrhea after hepatectomy and its impact on gastrointestinal quality of life in living donors. METHODS We...

tation from older living donors. Transplantation 2013; 95: 106–113 20. Fuggle SV, Allen JE, Johnson RJ et al. Factors affecting graft and patient survival after live donor kidney transplantation in the UK. Transplantation 2010; 89: 694–701 21. Chang P, Gill J, Dong J et al. Living donor age and kidney allograft half-life: implications for living donor paired exchange programs. Clin J Am Soc Nep...

OBJECTIVE To elicit donor opinions on liver living donation through use of a survey that protected the anonymity of the respondent and to assay long-term (follow-up > 1 year) donor health by a widely recognized instrument for health assessment. SUMMARY BACKGROUND DATA Living-donor liver transplantation is an accepted technique for children that has recently been extended to adults. Limited do...

Introduction At present, in the UK, live lobe donation of the lung is generally considered in the context of patients with cystic fibrosis (CF) which is a life-threatening, inherited disease. However, if this technique is successfully developed it may be applicable to other patients with end stage lung disease. Cystic fibrosis is a disease where the major morbidity and mortality is due to pulmo...

Careful evaluation of potential living kidney donors is crucial to assure the well being of the donors, especially because they do not gain any direct medical benefit from donation. This process also helps assess the quality and safety of the organs donated to the recipients. While all programs share these goals, donor selection criteria vary significantly among U.S. transplant centers. In part...

BACKGROUND Reduced kidney function confers a higher risk of acute kidney injury at the time of an inciting event, such as sepsis. Whether the same is true in those with reduced renal mass from living kidney donation is unknown. METHODS We conducted a population-based matched cohort study of all living kidney donors in the province of Ontario, Canada who underwent donor nephrectomy from 1992 t...

Kidney transplantation is a superior treatment strategy than chronic dialysis for end-stage renal disease patients. However, there is a severe shortage of cadaveric kidneys that are available for transplantation. Therefore many patients are turning to living donors. We describe four models of incentives to improve rates of living kidney donation: the market compensation model, the fixed compens...

PURPOSE OF REVIEW To hear from living kidney donors and recipients about what they perceive are the barriers to living donor kidney transplantation, and how patients can develop and lead innovative solutions to increase the rate and enhance the experiences of living donor kidney transplantation in Ontario. SOURCES OF INFORMATION A one-day patient-led workshop on March 10th, 2016 in Toronto, O...

from 1986 to 1996, 1020 renal transplants were performed at our center. the purposes of this study were. 1) to evaluate the patient and graft survival rates and 2) to see if some donors and recipient characteristics such as age, sex and relationship had any effects on graft survivals. 571 transplants were from living related donors (lrd) and 446 from living unrelated donors (lud). 65.9% of reci...

BACKGROUND Kidneys derived from brain-dead donors have inferior outcomes after transplantation compared to kidneys from living donors. Strikingly, early and profound serum levels of IL-6 in brain-dead donors are observed. IL-6 is the main regulator of the acute phase response (APR). The aim of this translational study was to investigate the expression of renal acute phase proteins (APPs) follow...