This article demonstrates the broad range of considerations that affect the outcome of patients undergoing hepatectomy. The progressive improvements in survival, despite the increasing complexity of the surgery, area testament to advances in both surgery and anesthesia. The key elements include careful patient selection, appropriate monitoring, and mechanical and pharmacologic protection of the...

Laparoscopic liver resection (LHR) has shown classical advantages of minimally invasive surgery over open counterpart. In spite of introduction in early 1990's only few centres worldwide adapted LHR to routine practice. It was due to considerable technical challenges and uncertainty about oncologic outcomes. Surgical instrumentation and accumulation of surgical experience has largely enabled to...

HYPOTHESIS The hand-assisted laparoscopic technique may be applied to the treatment of liver tumors. DESIGN A case series with mean follow-up of 13 months. SETTING University-affiliated tertiary care center. PATIENTS A total of 15 patients with hepatic neoplasms underwent screening tests, including appropriate tumor marker analyses, abdominal sonography, and computed tomographic scan and,...

Surgery is a crucial intervention and provides the best chance of cure for patients with colorectal cancer. Experimental clinical evidence, however, suggests that paradoxically surgery itself may precipitate or accelerate tumor recurrence and/or liver metastasis development. This review addresses various aspects surgery-induced formation sheds light on role inflammation as potential trigger Und...

Objective Resection of primary colorectal cancer is associated with enhanced risk of liver metastases development. We previously demonstrated that surgery initiated an early inflammatory response resulting in elevated tumour cell adhesion in the liver. Because reactive oxygen species (ROS) are shown to be produced and released during surgery, we now investigated the effects of ROS on liver vasc...

Implication for health policy/practice/research/medical education: Liver surgery and perioperative care of patients with hepatic dysfunction is still moving toward better safety. Anesthesiologists play their role with judicious selection of anesthetic medications. Ischemic liver injury occurs in a variety of clinical settings such as trauma, shock, and liver surgery (1, 2). Isch-emia and subseq...

Liver transplantation offers patients with liver disease an optimal chance for long-term survival. Current indications, preoperative assessment, patient selection, intraoperative anesthetic management and outcomes are described. The management of special situations, including retransplantation, pediatric transplantation, and fulminant hepatic failure are also reviewed. The success of liver tran...

Surgical procedures for the resection of pathologic lesions are often risky interventions. The risk concerns postoperative complications as well as the success of the operation in terms of its long-term effect. Postoperative complications may result if too much tissue is removed. The long-term effect depends on whether all lesions are detected and are removed entirely together with a saftey mar...