نتایج جستجو برای: liver lipids
تعداد نتایج: 366628 فیلتر نتایج به سال:
An impro&d, simplified procedure is described for the isolation of liver cells from rat or chicken. Livers were perfused in sifu and then incubated in a solution of collagenase and hyaluronidase. Greater than 50 % of the liver mass was converted into a suspension of intact parenchymal cells which excluded a vital stain and were undamaged when viewed with the electron microscope. The cells activ...
The incorporation of mevalonate into nonsaponifiable lipids by chick liver in vivo strongly increased between 1-18 days after hatching. Cholesterol feeding (2%) inhibited this. Synthesis of cholesterol was strongly inhibited, whereas the intermediates isolated by TLC accumulated. Most of the polar nonsaponifiable lipids that accumulated in liver 90 minutes after mevalonate administration to 18-...
Alcohol promotes accumulation of fat in the liver mainly by substitution of ethanol for fatty acids as the major hepatic fuel. The degree of lipid accumulation depends on the supply of dietary fat. Progressive alteration of the mitochondria, which occurs during chronic alcohol consumption, decreases fatty acid oxidation by interfering with citric acid cycle activity. This block is partially com...
Ethanol metabolism by liver generates short lived reactive oxygen species that damage liver but also affects distal organs through unknown mechanisms. We hypothesized that dissemination of liver oxidative stress proceeds through release of biologically active oxidized lipids to the circulation. We searched for these by tandem mass spectrometry in plasma of rats fed a Lieber-DeCarli ethanol diet...
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