liver injury drug

narges shahbazi department of pathology and laboratory medicine, cancer institute, imam khomeini hospital complex, tehran university of medical sciences, tehran, ir iran hayedeh haeri department of pathology and laboratory medicine, cancer institute, imam khomeini hospital complex, tehran university of medical sciences, tehran, ir iran mohsen nasiri toosi department of internal medicine, gastroenterology and hepatology division, imam khomeini hospital complex, tehran university of medical sciences, tehran, ir iran; liver transplantation research center, tehran university of medical sciences, tehran, ir iran ali jafarian liver transplantation research center, tehran university of medical sciences, tehran, ir iran; department of general surgery, hepatobiliary and liver transplantation division, imam khomeini hospital complex, tehran university of medical sciences, tehran, ir iran reza shahsiah department of pathology and laboratory medicine, cancer institute, imam khomeini hospital complex, tehran university of medical sciences, tehran, ir iran; liver transplantation research center, tehran university of medical sciences, tehran, ir iran monavar talebian moghadam liver transplantation research center, tehran university of medical sciences, tehran, ir iran

conclusions any discrepancy between histopathologic changes in time-zero biopsies and pattern of early liver laboratory alterations may be considered as a warning for causes other than pri. objectives the aim of this study was to show the correlation between histopathologic changes of pri and the alterations in liver tests in the early post-transplantation period. materials and methods between ...

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Advances in Engineered Liver Models for Investigating Drug-Induced Liver Injury

Journal: :BioMed Research International 2016

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Circulating Plasma and Exosomal microRNAs as Indicators of Drug-Induced Organ Injury in Rodent Models

2017

Young-Eun Cho Sang-Hyun Kim Byung-Heon Lee Moon-Chang Baek

This study was performed to evaluate whether microRNAs (miRNAs) in circulating exosomes may serve as biomarkers of drug-induced liver, kidney, or muscle-injury. Quantitative PCR analyses were performed to measure the amounts of liver-specific miRNAs (miR-122, miR-192, and miR-155), kidney-specific miR-146a, or muscle-specific miR-206 in plasma and exosomes from mice treated with liver, kidney o...

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