Wilson's disease (WD) is a disorder of copper metabolism leading to copper accumulation in the liver and in extrahepatic organs, such as brain and cornea. We present a patient with liver disease who did not fulfil the biochemical criteria for WD. Mutational analysis was necessary to make the diagnosis and show a new mutation. Our case supports the use of mutation analysis in cases with unclear ...

Lymphoproliferative disorders following liver transplantation are often Epstein-Barr virus (EBV)-related highgrade B cell lymphomas. EBV-negative and low-grade lymphoma is a very rare condition after cadaveric as well as living donor liver transplantation (LDLT). Herein we report a case of follicular lymphoma with negative EBV viral capsid antigen (VCA), IgM, IgG and Epstein-Barr virus-encoded ...

Non-alcoholic steatohepatitis (NASH) is a common liver disorder caused by fatty liver. Because NASH is associated with fibrotic and morphological changes in liver tissue, a direct imaging technique is required for accurate staging of liver tissue. For this purpose, in this study we took advantage of two label-free optical imaging techniques, second harmonic generation (SHG) and auto-fluorescenc...

Wilson's disease is an autosomal recessive disorder affecting copper transport; it results in the accumulation of copper in the liver, brain, and other organs. Wilson's disease is the most common inherited liver disease with more than 500 cases reported in Korea. An impairment in biliary excretion process leads to copper accumulation in the liver, which progressively damages the liver, leading ...

BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is the most common hepatic disorder, which poses a significant health burden in the western countries. As the epidemic of obesity slides health downward, the incidence of NAFLD is evidently increasing. AIM We aimed to ascertain the awareness of NAFLD and its risk factors in the general population, which may be helpful in designing education...

Polycystic liver disease (PCLD) is a rare autosomal dominant disorder which usually occurs in association with autosomal dominant polycystic kidney disease. Biliary obstruction is a rare complication of PCLD. Treatment options include percutaneous aspiration and sclerosis, surgical deroofing of cysts, liver resection or liver transplantation. Medical treatment involves the use of somatostatin a...

A 16-yr-old girl received liver transplantation for fulminant hepatitis. Aplastic anemia developed, and she received hematopoietic stem cell transplantation (HSCT). Eleven months after liver transplantation, abdominal lymph node enlargement and colon ulcers were observed, and colon biopsy showed posttransplant lymphoproliferative disorder (PTLD). Immunosuppression reduction was attempted, but i...

Focal nodular hyperplasia (FNH) of the liver is a benign disorder that usually occurs in women during their reproductive years. Multiple FNH is very rare. A case of multiple FNH of the liver occurring in a 34-year-old woman is described. FNH diagnosis was confirmed by means of US, CT, MR, scintigraphy and hepatic biopsy. There was no further change in either size or appearance of liver masses i...