We present a novel and simple method for inducing cell death. Cells placed in contact with paraffin or other hydrophobic-hydrocarbon substances die. Cell death can be the result of apoptosis, which is also known as programmed cell death (PCD). In apoptosis, cells shrink and undergo both disintegration of the nucleoli and nuclear fragmentation (2). In necrosis, cells swell and disintegrate. Apop...

Isobutyrate-1-(14)C and l-isoleucine-U-(14)C fed through the petiole labeled the surface lipids of broccoli leaves, but the incorporation was much less than from straight chain precursors. Not more than one-third of the (14)C incorporated into the surface lipids was found in the C(29) paraffin and derivatives, whereas more than two-thirds of the (14)C from straight chain precursors are usually ...

PURPOSE Mutations in the epidermal growth factor receptor (EGFR) are associated with clinical and radiographic responses to EGFR tyrosine kinase inhibitors gefitinib and erlotinib. Currently available methods of EGFR mutation detection rely on direct DNA sequencing, which requires isolation of DNA from a relatively pure population of tumor cells, cannot be done on small diagnostic specimens, an...

Deparaffinization is one of the stages tissue processing, which aims to dissolve paraffin for full-color application. can only be done by xylol as fat. Liquid laundry detergent has main component in form a surfactant property removing types lipids dissolving and emulsification because carcinogenic properties, flammable relatively expensive. This study aimed describe quality preparations using l...

Although the syndrome of an exogenous lipoid pneumonia due to aspirated liquid paraffin has been established for some four decades, it is evident from many of the published reports, mainly in the American literature, that the diag-nosis is still frequently being missed unless investigations are deliberately undertaken with this possibility in mind. Rewell (1947) published the -first probable ca...

The present work was aimed to develop an antiseptic cream formulation of Indian basil oil utilizing hydrophilic-lipophilic balance approach. In order to determine the required-hydrophilic lipophilic balance (rHLB) of basil oil, emulsions of basil oil were prepared by phase inversion temperature technique using water, Tween 80, and Span 80. Formulated emulsions were assessed for creaming (BE9; 9...

BACKGROUND Oronine H(®) ointment, which contains chlorhexidine gluconate as its active component, is a well known disinfectant, and has been widely used for treatment of acne in Japan. In this study, we investigated the inhibitory effect of this ointment on the formation of comedones induced by application of 50% oleic acid on the orifices of the external auditory canals of rabbits. METHODS T...