introduction: serum lipid disorders are one of the important risk factors for development of coronary arterial atherosclerosis. the aim of this study was to compare the effects of the drug lovastatin and a liquid vegetable extract (dill) on blood plasma lipid levels of rats. methods: in this experimental study, 32 mouse vistar rats weighing 250±30 grams were included and maintained at 23±1 degr...

background and objective type 2 diabetes mellitus is a chronic, progressive illness that causes considerable morbidity and mortality. despite recent technical advances in therapy, more people are using alternative therapies. in this study evaluated the effect of sodium metavanadate on glucose levels and lipid profile in type 2 diabetes mellitus patients.   methods this is a randomized, controll...

background: physical exercise and herbal treatment with antioxidant property induce a favorable effect on glucose metabolism in diabetic patients. the aim of the present study was to investigate the effects of resistance training combined with green tea extract consumption on blood glucose and lipid profile in diabetic rats. forty male wistar diabetic rats aged 5 months and weights 290 ± 20 wer...

background: obesity is associated with increased lipid peroxidation. it has also been suggested that risk of lipid peroxida­tion increases with increasing body iron stores. the aim of this study was to examine the association of body iron status with the concentration of plasma malondialdehyde (p-mda) as a marker of lipid peroxidation in obese and non-obese women. methods: in a case control stu...

the field of endocrine pharmacology is very wide but most of studies in the recent years from the world and iran have focused on diabetes, osteoporosis, and lipid disorders. in the present review, we tried to evaluate the improvements and publications in that field briefly. interestingly, many of studies have focused on agents that have traditional and natural origin. although few basic studies...

noise-induced hearing loss (nihl) is the most common complication of long-term noise exposure, though there  are  some  other  complications  due  to  exposure  to  noise.  metabolic  complications  of  the  noise exposure are being evaluated in recent studies. we aimed to assess the relationship between nihl and lipid profile, and fasting blood sugar (fbs). in this cross-sectional  study, 462 ...

abstract objective: the aim of this study was evaluating the relationship between maternal serum lipid measured at 13-23 weeks of pregnancy and subsequent glucose intolerance. materials and methods: in a prospective study, 624 pregnant women prior to 23 weeks were eligible for the study. primarily, serum levels of total cholesterol, ldl cholesterol, hdl cholesterol, and triglyceride were measur...

abstract diabetes mellitus is one of the major metabolic disorders. diabetes is recognized for severe complications including diabetic nephropathy, neuropathy and retinopathy. long-lasting effect of hyperglycemia results in increased oxidative stress. oxidative stress results from an imbalance between radical-generating and radical scavenging systems. increased oxidative stress has been shown t...

Lipid Nanoparticles In article number 2301929, Dan Peer and colleagues developed novel ionizable lipids for improved delivery of mRNA payloads. Rational lipid design together with in vivo screening identified lipid-based nanoparticles (LNPs) enhanced cell trophism. This study suggests that a structural combination tail linker can drive trophism LNPs vivo.