OBJECTIVE Insulin resistance is associated with increased triglyceride levels, low high-density lipoprotein cholesterol, small dense low-density lipoprotein (LDL), and increased apolipoprotein B (apoB) levels, all characteristics of familial combined hyperlipidemia (FCH). Therefore, we explored the role of insulin resistance in FCH lipid phenotype expression. METHODS AND RESULTS FCH was defin...

BACKGROUND Lipid disorders are common worldwide and contribute to a significant proportion of the burden of atherosclerotic cardiovascular diseases. OBJECTIVES To determine the prevalence of lipid disorders among patients reporting at Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana. DESIGN Cross-sectional study. SETTING Directorate of Medicine and Polyclinic outpatient clinics of KAT...

Recent studies suggest an association of obstructive sleep apnoea (OSA) with cardiovascular risk factors, such as dyslipidaemia. The present study analyses the effects of OSA and its therapy on serum lipid concentrations in 470 OSA patients in a single centre study. Multivariate regression showed a significant association between the apnoea-hypopnoea index and high-density lipoprotein cholester...

Experimental studies have demonstrated that for many marine invertebrate species, variability in larval condition or quality at settlement may have important effects on post-settlement, early juvenile performance. Relatively few studies, however, explicitly examine natural variability in larval condition at settlement. This study examines natural variability in larval attributes (size and lipid...

Background Abnormalities in total cholesterol (TC), high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), and triglycerides (TG) are associated with microvascular dysfunction. Recent studies suggest that lipoprotein sub-fractions better predict atherogenic burden than a routine lipid panel. We sought to determine, whether lipid sub-fractionation is associated with myocardial perfus...

type 2 diabetes mellitus is associated with increased inflammation and accelerated atherosclerosis. the association of the pro-inflammatory and potentially pro-atherosclerotic molecule, pregnancy associated plasma protein-a (papp-a) with diabetes and vascular diseases remains to be further established. a total of 107 patients with type 2 diabetes and 101 healthy controls participated in this st...

We demonstrate optical resolution photoacoustic microscopy (OR-PAM) of lipid-rich tissue using a multi-wavelength pulsed laser based on nonlinear fiber optics. 1047 nm laser pulses are converted to 1098, 1153, 1215, and 1270 nm pulses via stimulated Raman scattering in a graded-index multimode fiber. Multispectral PAM of a lipid phantom is demonstrated with our low-cost and simple technique.

BACKGROUND Integrated guidelines on cardiovascular health and risk reduction in children issued in 2011 newly recommended universal screening for dyslipidemia in children at 9 to 11 years and 17 to 21 years. METHODS AND RESULTS We determined the frequency and results of lipid testing in 301 080 children and adolescents aged 3 to 19 enrolled in 3 large US health systems in 2007 to 2010 before ...

This human study was conducted to evaluate the effect of chronic alcohol consumption on plasma concentrations of lipid and the antioxidative system in 44 Korean alcoholics and 45 age-, sex-, and nationality-matched nonalcoholic subjects. Plasma triacylglycerols and atherogenic index were higher in alcoholics than in control subjects. Plasma total cholesterol was not different among groups, but ...

Coronary artery disease is the epidemic of modern civilization in which dyslipidemia contributes significantly to its pathogenesis. We studied the significance of three important lipid ratios i.e. Atherogenic Index of Plasma (AIP) {(logTG)/HDLc}, Castelli’s Risk Index I & II (TC/HDLc and LDLc/HDLc respectively) and Atherogenic coefficient (AC) {(Non-HDLc)/HDLc} in predicting the risk of CAD. A ...