نتایج جستجو برای: line cells
تعداد نتایج: 1709978 فیلتر نتایج به سال:
objective: piwil2, a member of ago/piwi gene family containing piwi and paz domains, has been shown to be ectopically expressed in different cancer cells, especially its remarkable expression in cancer stem cells (cscs), and is also known to be essential for germ line stem cell self-renewal in various organisms. the hypothesis that csc may hold the key to the central problem of clinical oncolog...
introduction: setting up a system to study the in vitro hematopoiesis is helpful to understand the mechanism of hematopoiesis. the effects of several cytokines and hormones such as erythropoietin (epo) in differentiation of hematopoietic stem cells have been investigated in vivo. there are no records considering the potential differentiation of p19 cell line (embryonic carcinoma cells) to hemat...
Background: Neutrophils are the most abundant white blood cells in humans. Recently, a novel strategy called the formation neutrophil extracellular traps (NETs) was described. NETs is a new strategy for pathogen response. This study focused on whether LPS induced NETs release in vitro in the HL60 cell line. Methods: In this study, the HL60 cell line was used for culture and DMSO for induction ...
Introduction: In the present study, AS1411 aptamer conjugated gold nanoclusters (GNCs) have been introduced as a targeted radiosensitizer for enhancing megavoltage radiation therapy efficacy. RT has identified as an effective therapeutic modality for many different types of solid tumors. However, equal radiation beams absorption by tumor and surrounding healthy tissues is still...
Background: The chitinase-like protein, YKL-40, plays an important role in allergic diseases pathogenesis. Allergens induce its production from macrophages and epithelial cells. Some investigations indicated that loratadine has anti-inflammatory effects apart from its H1 receptors antagonist activity. We sought to know whether human epithelial cells and macrophages stimulated for YKL-40 synthes...
Background & Aims: Triple-negative breast cancer cells refer to any breast cancer that does not express the genes for the estrogen, progesterone, and HER2 receptors. The Wnt signaling pathway is important in the development and progression of various types of cancers. Quinacrine, a derivative of 9-aminoacridine, has been shown to inhibit the growth of several types of cancer cells. In this stud...
Application of nanotechnology in medicinal and biological fields has attracted a great interest in the recent yeras. In this paper the cell membrane leakage induced by iron nanoparticles (Fe-NP) against PC12 cell line which is known as a model of nervous system cell line was investigated by the lactate dehydrogenase (LDH) test. Therefore, PC12 cells were incubated with different concentration o...
Background: Conventional anti-cancer treatments, such as surgery, chemotherapy, radiation therapy, etc., are linked to antimicrobial resistance (AMR) and have negative effects on healthy tissues. Objectives: The flow cytometry technique was used in this study to evaluate the effectiveness of a modified anti-cancer peptide in treating the AGS gastric cancer cell line. Methods: This study used ...
Salvia chorassanica Bunge is one of the Iranian endemic species of Salvia. There is not any reported literature on S. chorassanica. This study was designed to examine the in-vitro anti-proliferative and proapoptotic effects of the methanol extract of S. chorassanica and its fractions on HeLa cell line. Cells were cultured in EX-CELL®, an animal free medium specially designed for HeLa cell line ...
Background: The cancer stem cells (CSCs) are involved in invasion and metastasis of melanoma, the most lethal and aggressive form of skin cancer. In the present study, the expression of putative stem cell markers CD133 and ALDH1 were evaluated in melanoma cell lines and then the cells sorted based on the expression of these markers. Methods: In the present study expression of CD133 and A...
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