background: ß-carbolines, harmaline and harmine, are the major alkaloids presenting in the seeds of the peganum harmala l. these alkaloids are known as herbal active principals with potential use in pharmaceutical and medicine. objectives: to assess the growth inhibitory effect of phyto-alkaloids, harmaline and harmine, on cancer cell lines. methods: the p. harmala l.’s alkaloids were extracted...

background: most cancer cells become resistant to anti-cancer agents. in the last few years, a new approach for targeted therapy of human cancer has been developed using immunotoxins which comprise both the cell targeting and the cell killing moieties. methods: in the present study, the recombinant shiga toxin a1 subunit fused to human granulocyte-macrophage colony stimulating factor (a1-gm-csf...

in this syudy a continuous bovine kidney cell line derived from a primary bovine kidney cells was established for the first time in iran. the cells were originating from two-day-old normal male calf of holstein breed. the cell cultures were continuously passaged following complete proliferation of primary cells. the specific properties or characteristics of the cell were defined using cytogene...

in order to determination the methionine requirement of arian broilers chickens during the starter period, a trial with 700 broiler chickens in a completely randomized design with 7 treatments, 5 replicates and 20 chicks in each experimental units was performed. experimental groups were consisted of 0.38, 0.43, 0.48, 0.53, 0.58, 0.63 and 0.68  % of methionine. other amino acids provided higher ...

air pollutants from iron and steel making operations have historically been an environmental concern. the factory located at ahwaz, iran, has two production lines namely, 630 and 650, which produce iron parallel edge. the objective of the study is to determine indoor respiratory particulate matter (rpm) and feo concentrations and their comparison with niosh standards. this is a cross–sectiona...

the current study was conducted to investigate the effect of short-term divergent selection on the shape growth curve in different lines of japanese quail. the quail lines utilized in this study were two divergently selected for high (hw) and low (lw) 4-wk body weight during 7 generation and also a control line (c). the richard function parameters were used to describe growth curves of differen...

Introduction: Hydroxyapatite nanoparticles inhibit the growth of various cancer cells. The inhibitory effect of these nanoparticles on breast cancer cells of mcf7 has also been reported. However, no studies have been done on the effect of the hydroxyapatite nanoparticles on the radiation sensitivities of the MCF7 cell Line. Our goal in this study is to investigate the effect of...

there are limited documents about hiv patients switched to second-line antiretroviral therapy (art) in resource-limited countries. we aimed to assess the efficacy of second-line art for hiv patients following first-line art failure. this was a cohort study of hiv/aids patients with first-line art treatment failure switched to second-line art between january 2004 and march 2014, who followed for...