introduction h syndrome (omim 612391) is an autosomal recessive disease with some features such as hyperpigmentation, hypertrichosis, heart anomalies, hepatosplenomegaly, hearing deficit, hypogonadism, short stature, flexion contracture of fingers and toes and hypertriglyceridemia. case presentation a 17-year-old boy with hyperpigmented, hypertrichotic and indurated seborrheic keratosis-like cu...

objective: fragile x syndrome is the second etiology for inherited mental retardation. it may concomitant with other psychiatric disorders. intellectual disability (id) is a state of functioning that typically begins in childhood and is characterized by limitations in intelligence and adaptive skills. we intend to introduce a male young patient with fragile x syndrome and obsessive-compulsive d...

the aim of this review is to focus the current knowledge about mental and behavioral disorders in usher syndrome. previous studies described the presence of various mental disorders associated with usher syndrome, suggesting possible mechanisms of association between these disorders. the most common manifestations are schizophrenia-like disorder and psychotic symptoms. mood and behavioral disor...

OBJECTIVE To describe theoretical weaknesses in the DSM-IV criteria for psychotic disorders and to argue that schizophrenia-like psychosis is a neurobiological syndrome similar to aphasia or apraxia. METHOD We outline the criteria for the concept of neurobiological syndrome and present supporting evidence for schizophrenia-like psychosis as a neurobiological syndrome. RESULTS There is evide...