introduction: sildenafil, a phosphodiesterase-5 (pde5) inhibitor, may have various effects on the central nervous system via the nitric oxide (no)-cyclic guanosine monophosphate (cgmp) pathway. preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals. this study was undertaken to investigate the acute effect of sildenafil on anxiety-like behavior...

Introduction: A neurodevelopmental disorder, autism typically identified with three primary behavioral consequences, such as social impairment, communication problems and limited or stereotypical behavior. Because of its co-morbidity and lack of therapeutic options, autism is a global economic burden. A short chain of fatty acid, propionic acid formed biologically by gut microbiome. Propionic a...

INTRODUCTION In October 2009, the first outbreak of pandemic influenza A(H1N1) 2009 virus  in Madagascar occurred at a school in Antananarivo. Among the first 12 cases, five were reported in boarding pupils at the school. The school closed 10 days into the outbreak. Mass oseltamivir prophylactic treatment was used to contain the outbreak. This study aimed to determine the transmission of infect...

Computer anxiety, as defined and operationalized in the human–computer studies literature, has been synonymous with negative thoughts and attitudes about the use of computers. This approach, together with correlational analyses that have formed the mainstay of research on computer anxiety, invokes two important points. First, it can be argued that computer anxiety, by definition, implies an att...

Human Perceptual Overestimation of Whole-Body Roll Tilt in Hyper-Gravity 1 2 Running title: Roll Perception in Hyper-Gravity 3 4 Torin K. Clark 5 Michael C. Newman 6 Charles M. Oman 7 Daniel M. Merfeld 8 Laurence R. Young 9 10 11 1 Man Vehicle Laboratory 12 Department of Aeronautics and Astronautics 13 Massachusetts Institute of Technology 14 Cambridge, MA, USA 15 16 2 Charles Stark Draper Labo...

Pedestrians are the most vulnerable road users. For evaluating and modifying pedestrian safety in unsignalized crosswalks,the first important issue is to identify and explore factors affecting the interaction behavior of pedestrians andvehicles in conflict areas. By analyzing those factors and determining how they affect road user's behavior, we canrepresent the plans and proc...