" If a tumour of this kind (pulsating encephaloid) be situated upon or under a large artery in the usual site of an aneurism, then the diagnosis is certainly replete with difficulty, and cannot indeed in many cases be made."?(Erichsen). Elahi Buksh, age 45 years, a weakly man in poor circumstances, came to the Dispensary on 5th February 1880, and gave the following history : Some 16 years ago h...

The traceless Staudinger ligation is an effective means to synthesize an amide bond between two groups of otherwise orthogonal reactivity: a phosphinothioester and an azide. An important application of the Staudinger ligation is in the ligation of peptides at a variety of residues. Here, we demonstrate that the traceless Staudinger ligation can be achieved in water with a water-soluble reagent....

Selective modification of carbohydrate residues in glycopeptides is highly relevant as a tool glycobiology. In particular, oxidation allows for subsequent ligation with label or handle and can be effectuated enzymatically chemically. Chemical nearly invariably done using periodate cleavage, leading to aldehydes. this work, we applied palladium-catalyzed the same purpose. The catalyst, [(neocupr...

Carbon nanotube electrodes were modified with ferrocene and laccase using two different click reactions strategies taking advantage of bifunctional dendrimers cyclopeptides. Using diazonium functionalization the efficiency oxime ligation, combination both multiwalled carbon surfaces or cyclopeptides allows access to a high surface coverage in order 50 nmol cm–2, 50-fold increase compared classi...

We describe the case of a 37-year-old woman who had undergone reversal of tubal ligation with subsequent heterotopic pregnancy. We review the initial radiological evaluation of heterotopic pregnancies and the subsequent radiologic findings following appropriate therapy.

Highly specific high-throughput assays will be required to take full advantage of the accumulating information about the macromolecular composition of cells and tissues, in order to characterize biological systems in health and disease. We discuss the general problem of detection specificity and present the approach our group has taken, involving the reformatting of analogue biological informat...

The anti-ulcer activity of Methanolic extract Myrica nagi (Myricaceae) fruit MEMN was investigated in pylorus ligation and methanol-induced ulcer models Wistar rats. In both models, the common parameter determined index at doses 200,400 mg/kg p.o produced significant inhibition gastric lesions induced by Aspirin-induced ulcers & ligation-induced ulcers. (200, 400 mg/kg) showed a (P < 0.0...

We studied the relation between [K+]o and the electrophysiologic changes during a "Harris two-stage ligation," which is an occlusion of a coronary artery, preceded by a 30-minute period of 50% reduction of flow through the artery. This two-stage ligation has been reported to be antiarrhythmic. Local direct current electrograms and [K+]o signals from up to 48 intramural sites were simultaneously...