نتایج جستجو برای: licorice

تعداد نتایج: 1072  

Journal: :American journal of epidemiology 2009
Katri Räikkönen Anu-Katriina Pesonen Kati Heinonen Jari Lahti Niina Komsi Johan G Eriksson Jonathan R Seckl Anna-Liisa Järvenpää Timo E Strandberg

Overexposure to glucocorticoids may link prenatal adversity with detrimental outcomes in later life. Glycyrrhiza, a natural constituent of licorice, inhibits placental 11-beta-hydroxysteroid dehydrogenase type 2, the feto-placental "barrier" to higher maternal levels of cortisol. The authors studied whether prenatal exposure to glycyrrhiza in licorice exerts detrimental effects on cognitive per...

Journal: :YAKUGAKU ZASSHI 1959

Journal: :Journal of Clinical Investigation 2005

Journal: :Molecules 2017
Jing Qiao Zuliang Luo Yanpeng Li Guangxi Ren Chunsheng Liu Xiaojun Ma

Licorice is one of the most generally used herbal medicines in the world; however, wild licorice resources have decreased drastically. Cultivated Glycyrrhiza uralensis Fischer are the main source of licorice at present, but the content of main active components in cultivated G. uralensis are lower than in wild G. uralensis. Therefore, the production of high-quality cultivated G. uralensis is an...

2014
Ulrike Grienke Heike Braun Nora Seidel Johannes Kirchmair Martina Richter Andi Krumbholz Susanne von Grafenstein Klaus R. Liedl Michaela Schmidtke Judith M. Rollinger

Neuraminidase (NA), a key enzyme in viral replication, is the first-line drug target to combat influenza. On the basis of a shape-focused virtual screening, the roots of Glycyrrhiza glabra (licorice) were identified as plant species with an accumulation of constituents that show 3D similarities to known influenza NA inhibitors (NAIs). Phytochemical investigation revealed 12 constituents identif...

Journal: :Fukushima journal of medical science 2014
Azusa Suganami Kazuho Sakamoto Tomoyuki Ono Hirotake Watanabe Nahoko Hijioka Masahiro Murakawa Junko Kimura

Shakuyakukanzoto (shao-yao-gan-cao-tang) is a commonly used Chinese traditional herbal medicine for the treatment of acute pain with muscle cramp. However, its mechanism of action is unclear. We previously reported that a low concentration of Kanzo (licorice) and isoliquiritigenin, a component of licorice, inhibited the potassium (K(+)) current in H9c2 cells. Therefore, in the present study, we...

2016
Enxiang Zhang Shutao Yin Xinhua Song Lihong Fan Hongbo Hu

Herbal medicine as an alternative approach in the treatment of disease has drawn growing attention. Identification of the active ingredient is needed for effective utilization of the herbal medicine. Licorice is a popular herbal plant that is widely used to treat various diseases including liver diseases. Glycycoumarin (GCM) is a representative of courmarin compounds isolated from licorice. In ...

Journal: :Biological & pharmaceutical bulletin 2005
Yasuharu Mizuhara Yukiho Takizawa Kazuhisa Ishihara Takayuki Asano Hirotaka Kushida Takashi Morota Yoshio Kase Shuichi Takeda Masaki Aburada Masaaki Nomura Koichi Yokogawa

In the course of our clinical studies of Kampo medicine (traditional Japanese medicines), we observed the pharmacokinetic interactions between two herbs. When Onpito (TJ-8117, Kampo medicine) containing licorice and rhubarb was administered orally to human subjects, we observed that the AUC(0-lim) and Cmax of glycyrrhetic acid (GA) in plasma were lower than those treated with other Kampo medici...

2015
Gita Faghihi Fariba Iraji Bahareh Abtahi-Naeini Bahar Saffar Ali Saffaei Mohsen Pourazizi Abolfazl Aslani Mohammad Ali Nilforoushzadeh

Hirsutism is one of the most prevalent health problems in women. The aim of the study was to compare the effect of 755 nm alexandrite hair removal laser with that of alexandrite laser plus topical licorice on the improvement of idiopathic hirsutism. A double-blind, randomized placebo-controlled study was performed on 90 female subjects. The patients were divided into two groups: alexandrite las...

Journal: :In vivo 2014
Hirokazu Ohno Shozo Miyoshi Daisuke Araho Taisei Kanamoto Shigemi Terakubo Hideki Nakashima Tadashi Tsuda Katsuyoshi Sunaga Shigeru Amano Emika Ohkoshi Hiroshi Sakagami Kazue Satoh Masaji Yamamoto

Compared to studies of water extracts of plants, those utilising alkaline extracts are limited. Both water and alkaline extracts from licorice root were compared regarding their biological activities. Licorice root was successively extracted first with water or alkaline solution (pH 9 or 12), and the alkaline (pH 12.0) extract was further separated into 50% ethanol-soluble and -insoluble fracti...

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