نتایج جستجو برای: levels of ifn
تعداد نتایج: 21200179 فیلتر نتایج به سال:
Pemphigus vulgaris (PV) is a chronic autoimmune blistering disease of the skin, in whichloss of adhesion between keratinocytes is caused by autoantibodies. It has been hypothesizedthat cytokines play an essential role in the pathogenesis of PV. This study aimed to investigatethe other immunopathological aspects of PV by determining the serum levels of cytokines inPV patients to find another tre...
conclusions results showed that hcvcp + bcg induced a moderate ctl and mixed th1/th2 immune responses with higher levels of cell proliferation and ifn-γ secretion, indicating that bcg may have a better outcome when formulated in hcvcp-based subunit vaccines. results expression and purification of core protein around the expected size (21 kda) was confirmed by western blotting. the hcvcp + bcg v...
interleukin (il)-35 is a newly discovered suppressive cytokine and has been shown to alleviate inflammatory and autoimmune diseases. the purpose of this study was to investigate immunomodulatory capacity of il-35 in patients with allergic asthma.il-35 mrna expression levels in peripheral blood mononuclear cells (pbmcs) were detected by quantitative real-time pcr (qpcr). the fr...
To investigate the effects of carvacrol supplementation diets in rainbow trout induced by LPS, we measured gene expressions relative to pro-inflammatory and apoptosis in kidney and liver. Fish, which that were studied by four different treatments with three replicates each, was 44.71±1.33 gr. All fish were infected with E. coli LPS (25 µg ml-1) expect control and only carvacrol containing diet ...
Objective: Paraquat (PQ) is a herbicide which induces oxidative stress and inflammation. Anti-inflammatory and anti-oxidant effects were shown for Zataria multiflora (Z. multiflora) and carvacrol previously. The effects of Z. multiflora hydroalcoholic extract and carvacrol on systemic inflammation and oxidative stressinduced by inhaled PQ were examine...
conclusions moderate exercise for 8 weeks increased the ifn-γ and decreased the il-17 serum levels in the morphine-dependent rats. for this reason, this type of exercise can improve the function of the immune system during morphine withdrawal syndrome. results after 8 weeks of exercise, a significant increase was observed in the serum ifn-γ level in the ht group (251.17 ± 13.045) in comparison ...
background:the premature termination of high producer clones, which will be killed due to cell proliferation and proteins production antagonism, is one of the basic drawback in recombinant proteins technology. furtheremore, it is supposed some toxic proteins like interferon which we intended to clone and express, inhibit host cells’ proliferation. so, it is necessary to tightly control ifn-γ pr...
Background: Sepsis is the leading cause of death in critically ill patients throughout the world. The incidence is increasing despite the major advances in the development of antimicrobial agents and other supportive treatments. Based on multiple studies, it has been shown that patient outcome depends on Th1 and Th2 cytokine response. Moreover, whenever the Th2 response is predominant, the seps...
having conducted the experiment and analysed the data, the researcher computed the groups mean scores and variances for the test relating to the research question. as the final atep, a t-test was conodonted for the hypothesis. as noted earlier, the significance level was determined at .05 and .01 respectively. the observed t-value was higher than the critical t-value at. 5 and .01 levels. conse...
Background: We explored the effect of vitamin D receptor gene (VDR) polymorphisms in response to PEG-IFN treatment in Egyptian chronic hepatitis B (CHB) patients. Methods: Two hundred hepatitis B virus (HBV) patients (42.3±10.7 years) on PEG-IFN α-2a (180 μg /kg for 48 weeks) and one hundred control subjects (37.3 ±12 years) were enrolled in the study. Vitamin D levels a...
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