OBJECTIVES To investigate patterns of self monitoring of blood glucose concentration in diabetic patients who use insulin and to determine whether frequency of self monitoring is related to glycaemic control. SETTING Diabetes database, Tayside, Scotland. SUBJECTS Patients resident in Tayside in 1993-5 who were using insulin and were registered on the database and diagnosed with insulin depe...

No AccessJournal of UrologyLetters to the Editor1 Jun 2021Microhematuria: AUA/SUFU Guideline. Letter. Matthijs N. Oyaert, Marijn M. Speeckaert, and Joris R. Delanghe OyaertMatthijs Oyaert Department Laboratory Medicine, Ghent University Hospital, Ghent, Belgium More articles by this author , SpeeckaertMarijn Speeckaert Nephrology, Research Foundation Flanders, Brussels, DelangheJoris * E-mail A...

Two new methods for the assay of total activities of lactate dehydrogenase and creatine kinase are described, in which the enzyme activities are measured from a solid-state reagent strip during a kinetic reaction, the reaction being monitored in the ultra-violet region of the spectrum by reflectance spectroscopy. The performances of these methods are evaluated, and compared to conventional "wet...

We describe the binding characteristics of two indicator dyes that are widely used in commercial "dip-stick" indicators for protein in urine. Binding was studied by both gel filtration chromatography and by spectrophotometric titrations. The results demonstrate that the well-known lack of sensitivity of these strips to proteins other than albumin relates to the number and affinity of binding si...

We examined a new colorimetric homogeneous immunoassay for carbamazepine based on the apoenzyme reactivation immunoassay system (ARIS) principle. The test, in dry-reagent strip format, is to be used with the Ames Seralyzer reflectance photometer. Within-run CVs (n = 20) were 3.0%, 2.7%, and 2.8% at 3.0, 6.1, and 12.1 mg/L; between-run CVs (n = 15, in 15 days) were 4.1%, 2.7%, and 1.9% at 6.0, 9...

Vitamin C (ascorbic acid), commonly taken as a dietary supplement and excreted in the urine, can interfere with peroxidase redox indicator systems such as those used in reagent-strip tests for urinary glucose and hemoglobin. We investigated whether the concentrations of ascorbic acid in urine after modest supplementary doses of vitamin C are high enough to interfere with such dipstick tests. Af...

BACKGROUND Preservatives that could prevent destruction of cells, casts, and bacteria in urine are of great practical importance because they allow centralization and improvement of accuracy of urine particle counting. We compared two in-house mixtures and one commercial solution, as well as refrigeration, for their ability to preserve urine for both automated analysis (flow cytometry) and visu...