The topical use of platelet concentrates is recent and its efficiency remains controversial. Several techniques for platelet concentrates are available; however, their applications have been confusing because each method leads to a different product with different biology and potential uses. Here, we present classification of the different platelet concentrates into four categories, depending o...

Leucocyte composition in the peripheral blood of brown trout Salmo trutta m. lacustris (L.) aged 1+ was studied in relation to Diphyllobothrium dendriticum (Cestoda) infection at two temperature levels, heated about 15 °C and non-heated which decreased from 11 °C to 7 °C. Blood samples were taken from control and infected fish 12 weeks post infection. The D. dendriticum infection (1–6 per fish)...

Leucocyte sodium and potassium content and concentrations were measured along with ouabain-sensitive and ouabain-insensitive rate constants for sodium efflux in 14 controls and 20 black patients with essential hypertension. Leucocyte sodium content was significantly increased in the patients (mean 101.1 +/- 7.8 mmol/kg dry solids v 74.5 +/- 7.6 mmol/kg dry solids; p less than 0.05), whereas the...

An abnormal filterability of whole blood through micropore membranes in vitro has been reported in peripheral vascular disease and has been thought to indicate abnormal red cell deformability. Blood from 68 patients with symptomatic peripheral vascular disease of varying severity and from 32 age-matched controls without a history of peripheral vascular disease was studied by the technique of wh...

The expression of the lymphoid marker, common leucocyte antigen and of the epithelial marker, epithelial membrane antigen by small cell anaplastic thyroid tumours was studied in 53 tumours, using the peroxidase--antiperoxidase and avidin--biotin techniques. Common leucocyte antigen was found in 33 of the 53 tumours; six tumours were positive for epithelial membrane antigen; and the remaining 14...

Chemokines play a key role in directing and driving leucocyte trafficking. The efficient regulation of leucocyte recruitment by chemokines requires their appropriate localization in functional micro-anatomical domains, as well as setting limits to their effects in space and time. Both processes are influenced by silent chemokine receptors (interceptors), including DARC (Duffy antigen receptor f...

Objective—To investigate the use of TcHMPAO (hexamethyl propylene amine oxime) leucocyte scintigraphy as a noninvasive screening test for inflammatory bowel disease. Patients—10 children with suspected Crohn’s disease, in whom routine investigation using barium contrast radiology, upper gastrointestinal endoscopy, colonoscopy, and mucosal biopsies had identified severe gastroduodenal and/or jej...

INTRODUCTION Little is known regarding systemic inflammatory response syndrome (SIRS) criteria and mortality in developing countries. We evaluated the utility of the SIRS criteria to predict death among a paediatric surgical population in Lilongwe, Malawi. METHODS Age, SIRS variables (temperature, heart rate, systolic blood pressure, respiratory rate and leucocyte count), diagnosis, surgical ...

A study was undertaken to investigate the effects of whole body chronic vibration on the immune system. Albino rats were exposed to whole body horizontal vibration acceleration 5.0 g, frequency 20 Hz for 3 hours per day for 3 months and changes were observed in plasma corticosterone level, total leucocyte count and differential leucocyte count. Neutrophil functions were accessed by candida phag...

The clinical value of Technitium-99TCm leucocyte in detecting early post-operative infection of prosthetic vascular grafts, to and from the femoral artery involving groin dissection is assessed. Twenty-five patients underwent bypass procedure using either Dacron or PTFE grafts. 99TCm labeled leucocyte scans were undertaken between 6-8 days following the bypass procedure. Fourteen patients had n...