In a double-blind crossover study, 8 patients with angina and with angiographically documented coronary artery disease received two weeks apart 5 successive doses of4 mg tolamolol (20 mg) and .5 successive doses of 2 mg propranolol (Io mg) administered intravenously within 25 minutes. After 20 mg tolamolol, a significant decrease occurred in heart rate (N4%), in aortic systolic pressure (4%), i...

OBJECTIVES The aim of this study was to investigate whether a new variable of mitral inflow, A wave deceleration time, identifies patients with elevated left ventricular filling pressures. BACKGROUND In patients with an elevated left ventricular end-diastolic pressure, the increase in left ventricular pressure after atrial contraction rapidly exceeds left atrial pressure, resulting in abrupt ...

Hemodynamic data of 167 patients of isolated ventricular septal defect (VSD) was retrospectively analyzed for the presence of left ventricular inflow gradients. End diastolic gradients of > 5 mm Hg between the pulmonary artery wedge pressure and the left ventricular end diastolic pressure were recorded in 40 of these patients. In three of these cases, left atrium was also entered and identical ...

Left ventricular high fidelity pressure measurements and simultaneous biplane cineangiocardiography were performed in 12 patients with severe aortic valve disease (aortic stenosis in 10, aortic insufficiency in 1 and combined valve lesion in 1). Left ventricular contractility was estimated from maximal rate of left ventricular pressure rise (max dP/dt), peak measured velocity of contractile ele...

To clarify the mechanism of displacement of the left ventricular diastolic pressure-volume function with alteration of loading conditions, the effects of nitroglycerin on pressure-volume relations in 13 patients were compared with those of amyl nitrite in 13 other patients during cardiac catheterization. After nitroglycerin, average systemic mean arterial pressure declined by 15.1 mm Hg (17%) a...

Left ventricular function was assessed by angiographic methods in 40 patients (ages 3-27), 1-12 years following repair of tetralogy of Fallot. Twenty of the 40 patients (group A) had a satisfactory repair with a pulmonary-systemic flow ratio (Qp/Qs) less then or equal to 1.5 and a right ventricular systolic pressure of less than or equal to 60% of the left ventricular value. The other 20 patien...

OBJECTIVE Blood pressure variation throughout the day is known to have cardiovascular consequences. Left ventricular (LV) mass is more closely related to 24-hour blood pressure than casual blood pressure. Daytime blood pressure expectedly is higher than that of nighttime under normal circumstances. The effect of 24-hour blood pressure pattern on the left ventricular structure and function has n...

background: the prevalence of patients with severe left ventricular dysfunction (lvd) referred for coronary artery bypass grafting (cabg) is increasing. preoperative lvd is an established risk factor for early and late mortality after revascularization. the aim of the present study was to assess the early outcome of patients with severe lvd undergoing cabg. methods: between december 2012 and no...

introduction: left ventricular ejection fraction (lvef) is considered to be the single most important prognostic factor in patients with previous myocardial infarction. lvef is not improved in all patients after coronary artery bypass grafting (cabg). this study aimed to assess the possibility of prediction of lvef changes after cabg using myocardial perfusion gated signle photon emission compu...

To determine the effects of steady-state left ventricular systolic pressure alterations on radionuclide measures of left ventricular filling dynamics, we studied 15 normal patients and 17 patients with nonischemic heart disease. Micromanometer left ventricular pressures and computer assisted forward gated radionuclide angiograms were acquired simultaneously. Right atrial pacing maintained heart...