Surface potentials of mixed monolayers of dicetyl phosphate and eicosanyl trimethylammonium bromide (1:1) were the same on subsolutions of 0.02 M NaCl or 0.01 M CaCl(2), which indicated that ionic phosphate does not interact with Ca(++) in the presence of a neighboring trimethylammonium group. Surface potential-pH plots of dicetyl phosphate, and of dipalmitoyl, egg, and dioleoyl lecithins showe...

The biliary excretion rates of bile acid, lecithin, and cholesterol were measured in unanesthetized dogs after interruption of enterohepatic circulation and during infusions of sodium taurocholate, sodium glycocholate, sodium dehydrocholate, SC2644 (a bicyclic organic acid with high choleretic potency), and secretin. Both lecithin output and cholesterol output were directly related to bile acid...

Fluorescence polarization measurements of microviscosity (apparent viscosity within the hydrophobic center of lipid bilayers) of amniotic fluid correlate well with lecithin/sphingomyelin ratios determined by thin-layer chromatography. In addition to lecithin, phosphatidylglycerol and phosphatidylinositol are important for determining fetal lung maturity, but the lecithin/sphingomyelin ratio giv...

Lecithin-rich mixtures of the nontoxic surfactants lecithin and Tween 80 are effective marine oil spill dispersants, but produce much higher oil-water interfacial tension than other, comparably effective dispersants. This suggests interfacial phenomena other than interfacial tension influence lecithin-Tween 80 dispersants' effectiveness. The interface between seawater and dispersant-crude oil m...

Human subjects were infused intraduodenally with either lecithin (150 mg/kg/hr) or safflower oil (100 mg/kg/hr)of similar fatty acid composition, and plasma lipoproteins were studied when constant plasma lipid levels were reached. Both types of fat induced increases of lipoproteins of Sf > 400 (chylomicrons) and Sf 20--400 (VLDL). Lecithin infusions produced increases predominantly in VLDL, whe...

Incorporation of acetate-1-(14)C into phospholipids and fatty acids by lung slices from fetal and newborn lambs and from ewes was studied in vitro. The distribution of radioactivity in the fatty acids of neutral lipids, phospholipids, and lecithin was determined. Acetate-1-(14)C was incorporated into myristic, palmitic, and C(18) fatty acids. Of the lecithin fatty acids, myristic and palmitic w...

However, a scrutiny of all the work on lecithin reveals a remarkable incompleteness of each individual investigation. A rigorous proof of the accepted theory requires for lecithin an element,ary composition of C = 65.60, H = 10.79, N = 1.74, P = 3.86. It further requires that the nitrogen of the molecule should be composed entirely of choline. Hence, lecithin should not contain even a part of i...

Rabbit polymorphonuclear leukocytes ingesting paraffin oil particles stabilized with albumin, converted more lysolecithin-(32)P (added to the medium as an albumin complex) to cellular lecithin than did control cells. Almost all of the increment in leukocyte lecithin-(32)P is found in association with the isolated phagocytic vacuoles. About half of lecithin-(32)P of granulocytes incubated first ...