Effect of polyherbal formulation Ambrex was evaluated in butylated hydroxytoluene (BHT) induced toxicity of lungs and liver in rats. Toxicity was produced by administering BHT (500 mg/kg/day) for 3 days. Lung damage was evidenced by elevated levels of broncho alveolar lavage fluid (BAL) parameters such as protein, lactate, lactate dehydrogenase (LDH), alkaline phosphatase (ALP), acid phosphatas...

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The present study was aimed to evaluate the therapeutic potential of Pimpinella tirupatiensis (Pt) by assaying the activities of selective mitochondrial enzymes in streptozotocin induced diabetic rats. Diabetic rats showed a significant (p < 0.01) reduction in the activities of oxidative enzymes Succinate dehydrogenase (SDH), Malate dehydrogenase (MDH), Glutamate dehydrogenase (GDH) and isocitr...

The effect of biopesticide - Derisom on certain metabolites and enzymes of carbohydrate metabolism were evaluated in gill, liver, kidney and muscle of Cyprinus carpio during sub-lethal toxicity exposure of 21 days. A dose of 0.28 ppm was taken as the sub-lethal dose. The organs were taken from exposed and control fish at the end of 24 hrs, 7, 14 and 21 days and used for the estimation of total ...

Vitamin C and taurine (TR) are well known as active components for fatigue recovery. However, the mechanism of anti-fatigue effects vitamin TR is still unclear. Our study was designed to evaluate activities in an animal test compare between TR. Materials Methods: C, or their combination were orally administrated mice once daily 15 days, then metabolic such blood glucose, triglyceride (TG), lact...

D-Lactate is oxidized by two classes of D-lactate dehydrogenase (D-LDH), namely, NAD-dependent and NAD-independent D-LDHs. Little is known about the characteristics and biological functions of D-LDHs in rice. In this study, a functional NAD-independent D-LDH (LOC_Os07g06890) was identified in rice, as a result of alternative splicing events. Characterization of the expression profile, subcellul...

In this study we examined the serum activity of lactate dehydrogenase (LDH) and its isoenzyme patterns in 28 calves of a lowland black spotted breed and its crossbreeds at the age of 2-6 months suffering from clinically noticeable manifested respiratory diseases--bronchopneumonia (BRD Group). As a control group we used 35 clinically healthy calves of the same age, breed and nutrition (Healthy G...

Differential expression of isozymes enables fish to tolerate temperature fluctuations in their environment. The present study explores the modulation lactate dehydrogenase (LDH) and cytoplasmic malate (sMDH) isozyme heart, muscle, brain, liver, gill, kidney juvenile Horabagrus brachysoma after 30 days acclimation at 26, 31, 33, 36°C. LDH sMDH zymography were performed using native polyacrylamid...

Enzymes have become important tools in several industries due to their ability to produce chirally pure and complex molecules with interesting biological properties. The NAD(+)-dependent LDH (lactate dehydrogenase) [bsLDH [Geobacillus stearothermophilus (formerly Bacillus stearothermophilus) LDH] from G. stearothermophilus and the NAD(+)-dependent FDH (formate dehydrogenase) [cmFDH (Candida met...

Pyrroloquinoline quinone (PQQ), a redox-active o-quinone, is an important nutrient involved in numerous physiological and biochemical processes in mammals. Despite such beneficial functions, the underlying molecular mechanisms remain to be established. In the present study, using PQQ-immobilized Sepharose beads as a probe, we examined the presence of protein(s) that are capable of binding PQQ i...