The molecular basis for the difference in the strength of T cell responses to self vs alloantigens is unknown, but may reflect how T cells are selected in the thymus. Because T cells with a high affinity for foreign as opposed to self MHC molecules are able to mature, it has been proposed that alloreactive T cells may be more strongly dependent upon interaction with MHC residues than are self-r...

We study the complexity theory for the local distributed setting introduced by Korman, Peleg and Fraigniaud in their seminal paper [3]. They have defined three complexity classes LD (Local Decision), NLD (Nondeterministic Local Decision) and NLD. The class LD consists of all languages which can be decided with a constant number of communication rounds. The class NLD consists of all languages wh...

To better understand the biological implications of the association of ligand with major histocompatibility complex class I molecules, we have studied the Ld molecule of the mouse. The culturing of various nonselected cell lines with three different known Ld peptide ligands resulted in a two- to fourfold specific increase in surface Ld expression as detected by 10 of 11 different monoclonal ant...

Interindividual variability in the glucuronidation of xenobiotics metabolized by UDP-glucuronosyltransferase 1A9 (UGT1A9) suggests the presence of functional UGT1A9 variants. The aim of this study was to evaluate whether the putative functionality of the UGT1A9 variants-118T(9>10) (rs3832043), I399C>T (rs2741049), -275T>A (rs6714486), and-2152C>T (rs17868320) could be confirmed in an independen...

Junctional sequences created by chromosomal translocations in mature B-cell neoplasms, which involve immunoglobulin gene loci (IG) and putative proto-oncogenes on reciprocal partner chromosomes, are unique to neoplastic cells characterized by particular histological and immunological phenotypes. To establish a rapid and sensitive method to detect neoplastic cells carrying a specific chromosomal...

Bu çal??man?n amac? yabanc? dil olarak Türkçe ö?retimi ders kitaplar? üzerine yap?lan ara?t?rmalar? çe?itli aç?lardan incelemektir. Nitel ara?t?rma deseninde doküman incelemesiyle gerçekle?tirilen ara?t?rmada 2010-2020 y?llar? aras?nda yay?mlanm?? 100 makale ve 142 lisansüstü tez olmak üzere 242 çal??ma incelemeye al?nm??t?r. Ara?t?rma bulgular?na göre en fazla 2019 2018 y?llar?nda yap?ld??? be...

I n my c o lu m n fo r t h e fa l l 2 0 1 2 n e ws le t t e r, I s h a re d s o m e t h o u gh ts t h a t I h o p e d wo u ld b e u s e f u l to j u n i o r fa c u lty m e m b e r s fa c e d w i t h n av i ga t i n g t h e tr i c k y wa te r s o f t h e academy. Four people to ld me they l i ked the column. This outcome far exceeded my expectat ions , so I chose to wri te on th is theme again f...

Amaç: Çin Halk Cumhuriyeti (ÇHC)’nde Sovyet Revizyonizmi olarak adland?r?lan ve Marksizm’e ihanet de?erlendirilen Kru?çev’in politikalar?, So?uk Sava? içerisinde Çin-Sovyet Ayr?l??? bilinen dönemin ba?lamas?na yol açm??t?r. Bu dönemde ÇHC, Revizyonizmi’ne kar?? propagandaya giri?mi?, halk?n?n yönelik fikirlerden uzak durmas?n? amaçlam??t?r. Propaganda sürecinde Marksist-Leninist temelli kitapla...