Background. This study performed a critical analysis of signal-averaging methods. The objective was to optimize detection of late potentials. Methods and Results. We studied two patient populations: a low-arrhythmia-risk group with no evidence of heart disease and a group with clinically documented ventricular tachycardia (VT). Filtered QRS duration (QRSD) and terminal QRS amplitude (RMS40) wer...

1. Single-electrode current- and voltage-clamp techniques were employed to study properties of the conductance underlying an orthodromically evoked late synaptic hyperpolarization or late inhibitory postsynaptic potential (IPSP) in CA3 pyramidal neurons in the rat hippocampal slice preparation. 2. Late IPSPs could occur without preceding excitatory postsynaptic potentials at the resting membran...

Above recruitment threshold, ocular motoneurons (Mns) show a firing rate linearly related with eye position. Current hypothesis suggests that synaptic inputs are determinant for establishing the recruitment threshold and firing rate gain in these Mns. We investigated this proposal by studying the cholinergic modulation in oculomotor nucleus Mns by intracellular recordings in rat brain slice pre...

Behavioral and physiological studies show that neuronal interactions among the glomeruli in the insect antennal lobe (AL) take place during the processing of odor information. These interactions are mediated by a complex network of inhibitory and excitatory local interneurons (LNs) that restructure the olfactory representation in the AL, thereby regulating the tuning profile of projection neuro...

A masking level difference (MLD) paradigm was used to investigate the presence of an electrophysiologic correlate of the psychoacoustic MLD in the middle and late auditory evoked potentials. In experiment 1, middle latency potentials were recorded in six normal-hearing young adults using vertex and temporal electrode montages. Tone bursts of 500 Hz presented in SoNo and Spi No conditions produc...

Facial attractiveness is of high importance for human interaction and communication, and everyday experience suggests that the mere aspect of a face elicits spontaneous appraisal of attractiveness. However, little is known about the time course of brain responses related to this process. In the present study, event-related brain potentials were recorded during attractiveness classification of f...

OBJECTIVE To evaluate the frequency, clinical correlations and prognosis influence of late potentials on the of heart failure patients with different etiologies using the signal averaged electrocardiogram. METHODS A 42 month study of the signal averaged electrocardiograms of 288 heart failure patients with different etiologies was conducted. The group of patients included 215 males (74.65%) a...

Familiarity and recollection are qualitatively different explicit-memory phenomena evident during recognition testing. Investigations of the neurocognitive substrates of familiarity and recollection, however, have typically disregarded implicit-memory processes likely to be engaged during recognition tests. We reasoned that differential neural responses to old and new items in a recognition tes...

Previous studies have demonstrated that in the hippocampus the maintenance of long-term potentiation (LTP) requires de novo protein synthesis. To investigate the role of protein synthesis in the maintenance of LTP of C-fiber evoked field potentials in spinal dorsal horn, which may be relevant to hyperalgesia, protein synthesis inhibitor (either cycloheximide or anisomycin) was applied locally t...

In the present paper, the expressions for scalar and vector potentials in lossless isotropic chiral media are analyzed. Propagating eigenvalues of these potentials are then obtained. Furthermore by decomposition of sources and fields in a chiral medium, we introduce the auxiliary right-and left-handed potentials and find the associated fields. These potentials are used to solve the problem of a...