Abstract Background Histoplasmosis is an endemic granulomatous fungal infection which rarely infects the larynx; less than 100 cases have been reported in medical literature till date. Case presentation A 6-year-old female child, a diagnosed case of B cell acute lymphoblastic leukemia since past 2 years and on chemotherapy, presented with hoarseness dysphagia months. Direct laryngoscopy reveale...

Multiple imaging modalities are used to obtain qualitative and quantitative data on laryngeal height and state during pharyngeal consonant production. Videofluoroscopy provides insight into the relative changes in pharyngeal and epilaryngeal lumina, allowing us to compare the roles these structures play in epilaryngeal constriction. Simultaneous laryngoscopy and laryngeal ultrasound allow us to...

The simultaneous assessment of the status of the glottis opening and the position of the larynx can be beneficial for the diagnosis of disorders of voice production and swallowing. The method presented here makes use of a time-multiplex algorithm for the measurement of space-resolved transfer impedances through the larynx. The fast sequence of measurements allows a quasi simultaneous assessment...

OBJECTIVE To compare outcome of patients with advanced laryngeal hypopharyngeal squamous cell carcinoma treated surgically or with chemotherapy and/or radiotherapy. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY The Aga Khan University Hospital, Karachi, from January 2000 to December 2005. METHODOLOGY Medical records of already treated stage-III and IV squamous cell carcino...

In cases of articulatory conflict, gestures involved in preserving phonemic distinctiveness are generally favored over gestures that do not. Here, an apparent exception to the phonemic distinctiveness preservation hypothesis is shown to in fact conform to it: in English, the larynx is lowered before voiced stops to maintain voicing distinctiveness, but the larynx is raised during high vowels, a...

Digital video filming of the thryroid prominence was used to measure larynx height in German vowels, with focus on contrasts involving front unrounded, front rounded and back rounded vowels. The study aimed to provide a foundation for interpreting the acoustic consequences of articulatory manoeuvres not only at the larynx but also elsewhere in the vocal tract. Results showed the expected patter...

Introduction: Isolated amyloidosis of the larynx is rare, being the single most common location in head and neck. Can be divided into diffuse and nodular, and the surgical treatment priority. Objective: To describe a case of isolated nodular amyloidosis of the larynx, with review of literature. Case report: A female patient, 23 years, presented with complaints of dysphonia and cervical cake for...

Optical coherence tomography OCT is an evolving noninvasive imaging modality and has been used to image the larynx during surgical endoscopy. The design of an OCT sampling device capable of capturing images of the human larynx during a typical office based laryngoscopy examination is discussed. Both patient’s and physician’s movements were addressed. In vivo OCT imaging of the human larynx is d...

OBJECTIVE This study aimed to: assess the mucosal alterations of the larynx and hypopharynx typical for mucopolysaccharidoses, in a standardised manner; compare the severity in different subtypes of mucopolysaccharidoses; and monitor the effect of an enzyme replacement therapy. METHODS A classification for mucosal alterations of the larynx and hypopharynx was developed and utilised in 55 pati...