Pharmacogenetics offers the prospect of an era of safer and more effective drugs, as well as more individualized use of drug therapies. The effect of human genetic variance on responses to therapy will influence drug-development clinical trials and the use of products in clinical practice. It also promises to raise new ethical challenges, in particular in the fields of research and therapy. Las...

The vision for the special issue in Brain and Cognition is rooted in the need to bring to the foreground the state of scientific knowledge in research and clinical neuroimaging ethics. To this end, the issue highlights a broad range of relatively unexplored ethical challenges in functional neuroimaging with MR, alone or in combination with other neuroimaging modalities, from imaging the central...

Non-treatment decisions concerning demented patients are complex: in addition to issues concerning the health of patients, ethical and legal issues are involved. This paper describes a method for the development of a guideline that clarifies the steps to be taken in the decision making process whether to forgo curative treatment of pneumonia in psychogeriatric nursing home patients. The method ...

Utilitarianism and quality-of-life considerations have increased the pressure to devalue life in terminal situations, leading to ethical confusion among caregivers. Where is the balance between a commitment to life and a commonsense willingness to "let go" when the time comes? This paper explores this balance, using a case history of a man with respiratory failure. This provides an opportunity ...

Journal of Hospice & Palliative Nursing: August 2021 - Volume 23 Issue 4 p E17 doi: 10.1097/NJH.0000000000000781

An international working group was established with the aim of making recommendations on the number of offspring for a sperm donor that should be allowable in cases of international use of his sperm. Considerations from genetic, psychosocial, operational and ethical points of view were debated. For these considerations, it was assumed that current developments in genetic testing and Internet po...

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Advancements in maternal–fetal interventions have allowed for direct fetal access, shifting the focus of from maternal health to a on sole fetal/neonatal benefit. Given that access fetus can only be obtained through mother, there are ethical considerations important consider when counseling dyad. The goals range improved survival decreased long-term morbidities and quality life. However, improv...