Collective migration of epithelial cells underlies diverse tissue-remodeling events, but the mechanisms that coordinate individual cell migratory behaviors for collective movement are largely unknown. Studying the Drosophila follicular epithelium, we show that the cadherin Fat2 and the receptor tyrosine phosphatase Lar function in a planar signaling system that coordinates leading and trailing ...

O artigo objetivou compreender o processo de socialização profissional da mulher em espaços políticos. Utilizou-se pesquisa exploratória qualitativa, com dez entrevistas profundidade vereadoras e deputadas, realizadas por meio roteiro semiestruturado pautado nas três fases (HUGHES; 1958; DUBAR, 2005): “Passagem através do espelho”, “Instalação dualidade” “Ajuste concepção si”. Notou-se que as m...

BACKGROUND The aims of the current study were: a) to quantitatively compare data obtained by Short Message Service (SMS) with data from a telephone interview, b) to investigate whether the respondents had found it acceptable to answer the weekly two SMS questions, c) to explore whether an additional weekly third SMS question would have been acceptable, and d) to calculate the total cost of usin...

plagioclase and spinels in LAR 06319. Fig. 1: Thin-section photomicrograph of LAR 06319, 37, in transmitted light. Olivine-Phyric Shergottite LAR 06319: Its relation to the enriched components in Martian basalts. A. Basu Sarbadhikari 1,2 , J.M.D. Day 3 , Y. Liu 1 , and L.A. Taylor 1 ; 1 Planetary Geosciences Institute, Dept. of Earth & Planetary Sciences, Univ. of Tennessee, Knoxville, TN 37996...

This work presents a low-aspect-ratio (LAR) inertial microfluidic design compatible with roll-to-roll (R2R) hot embossing for size-based cell or microparticle separation in a low-cost and disposable format. The device consists of two segments of LAR channels in which inertial lift forces are used to differentiate lateral positions based on size for separation downstream. Separation of 18μm and ...

PURPOSE To compare organ specific cancer incidence risks for standard and complex external beam radiotherapy (including cone beam CT verification) following breast conservation surgery for early breast cancer. METHOD Doses from breast radiotherapy and kilovoltage cone beam CT (CBCT) exposures were obtained from thermoluminescent dosimeter measurements in an anthropomorphic phantom in which th...

The compatibility of a 2% chlorhexidine gluconate/70% isopropyl alcohol (CHG/IPA) skin preparation with a gum mastic liquid adhesive (GMLA) and liquid adhesive remover (LAR) was assessed in healthy volunteers. Twenty subjects completed test material combination with microbial sampling at 3- and 7-day time points. Mean log10 reductions from baseline for normal flora were assessed. There was no s...

BACKGROUND Octreotide treatment may be associated with gall stone development in up to 50% of patients with acromegaly. Two new sustained-release formulations of somatostatin analogue have been recently developed: lanreotide SR (Somatuline) and octreotide LAR (Sandostatin LAR). The incidence of gall-stone development in patients receiving these drugs has been shown to be less than 20%, but the ...

OBJECTIVE To determine whether the somatostatin receptor subtype (SSTR) expression profile correlates with hormonal and tumor volume responses to postsurgical octreotide long acting repeatable (OCT LAR) treatment. DESIGN AND METHODS Quantitative real-time RT-PCR was used to evaluate the absolute mRNA copy numbers for all five SSTR subtypes in 22 somatotropinomas. Response to OCT LAR was studi...

Most receptor-like protein tyrosine phosphatases (PTPases) display a high degree of homology with cell adhesion molecules in their extracellular domains. We studied the functional significance of processing for the receptor-like PTPases LAR and PTPsigma. PTPsigma biosynthesis and intracellular processing resembled that of the related PTPase LAR and was expressed on the cell surface as a two-sub...