نتایج جستجو برای: langerhans islets

تعداد نتایج: 16514  

2015
Constantin Ionescu-Tirgoviste Paul A. Gagniuc Elvira Gubceac Liliana Mardare Irinel Popescu Simona Dima Manuella Militaru

Islets of Langerhans are fundamental in understanding diabetes. A healthy human pancreas from a donor has been used to asses various islet parameters and their three-dimensional distribution. Here we show that islets are spread gradually from the head up to the tail section of the pancreas in the form of contracted or dilated islet routes. We also report a particular anatomical structure, namel...

Journal: :Transplantation proceedings 1992
P B Carroll C Ricordi H R Rilo P Fontes R Khan A G Tzakis R Shapiro J J Fung T E Starzl

I N PATIENTS with type I diabetes. insulin production by pancreatic islets declines until severnl years after onset, and the majority have no demonstrable endogenous insulin secretion due to relentless autoimmune destruction of insulin-producing B cells. Before 1990, the lack of any successful islet cell transplants in humans was frustrating. With new developments in the techniques used to isol...

Journal: :Tissue Engineering Part C: Methods 2009

Journal: :Journal of Biological Chemistry 1968

Journal: :Journal of Biological Chemistry 2011

Journal: :Diabetes 1953
F D W LUKENS

factor; here according to current concepts the pituitary growth hormone may play an important part. In the case of the "pre-diabetic fathers," the factor of inheritance must be the determining factor. Jackson contends that when a woman gives a history of having had several large babies, the diagnosis of a pre-diabetic state is justified to such an extent that treatment should be started before ...

Journal: :Biophysical journal 2014
Raghuram Dhumpa Tuan M Truong Xue Wang Richard Bertram Michael G Roper

Insulin is released from the pancreas in pulses with a period of ~ 5 min. These oscillatory insulin levels are essential for proper liver utilization and perturbed pulsatility is observed in type 2 diabetes. What coordinates the many islets of Langerhans throughout the pancreas to produce unified oscillations of insulin secretion? One hypothesis is that coordination is achieved through an insul...

2000
Milan Jamrich Ming-Jer Tsai Hsiang-Po Huang Min Liu Heithem M. El-Hodiri Khoi Chu MIN LIU HEITHEM M. EL-HODIRI KHOI CHU MILAN JAMRICH

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