<p class="abstract">Langerhans cell histiocytosis is a condition of exceptional onset characterized by proliferative event dendritic cells with mono or multisystem involvement that predominates in the pediatric population and identified smaller proportion adults. It has clinical impact variable prognosis according to its location number organs affected. A 68-year-old male patient immunohi...

The report presents a case of Langerhans cell histiocytosis with diagnostic problems and fatal outcome in a 3-year-old girl, as well as a short literature review.

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by high proliferation of Langerhans dendritic cells. LCH is a solitary or multifocal disease that primarily involves bone tissue and often affects children and young men. A 29 years-old Caucasian man was referred to the Oral Surgery Unit of George Eastman Hospital - Umberto I teaching hospital, with third degree mobility of te...

BACKGROUND Langerhans cell histiocytosis (LCH) is a proliferative disease of histiocyte-like cells that generally affects children. Immunohistochemistry is essential to obtain the correct diagnosis, and treatment protocols are controversial. OBJECTIVE Langerhans cell histiocytosis (LCH) is easy to be misdiagnosed because of its various clinic features and laboratory results. This research foc...

Cigarette smoking is a major risk factor for pulmonary Langerhans cell histiocytosis (pLCH) and lung cancer. Resolution of pLCH may occur spontaneously, after smoking cessation or other interventions. However, despite clinicoradiological resolution, residual pulmonary Langerhans cells may be present and may lead to recurrent disease. We report the first case of pLCH with a complete histological...

INTRODUCTION Langerhans cell histiocytosis (LCH) is a rare atypical cellular disorder characterized by clonal proliferation of Langerhans cells leading to myriad clinical presentations and variable outcomes. It usually occurs in children and young adults. It can be present with local and systemic manifestation involving skin, bone, mucosal tissues and internal organs. AIMS AND OBJECTIVES The ...

Langerhans cell histiocytosis (LCH) is a rare disease in which Langerhans cells, which are bone marrow-derived antigen-presenting cells, proliferate in single or multiple organs. We successfully treated a patient with unifocal LCH of the mandible with malocclusion due to a severe pathological fracture, using reconstruction with a vascularised free bone.

We report a patient with vulvar lichen sclerosus, Langerhans cell histiocytosis (LCH), and later vulvar cancer. In LCH, high amounts of non functional Langerhans cells are present in the affected tissue, making it possible that LCH may have contributed to vulvar cancer development in this patient.

Pulmonary Langerhans cell histiocytosis is a rare interstitial lung disease. It's morbidity is estimated at 4-5 person per million. The multiformity--from benignity to severe--brings difficulties during the process of diagnosis. The authors describe a case of 48-year-old woman with a benign pulmonary lung histiocytosis. It is underlined the diagnostic quality of high resolution tomography and b...

Received 2/6/2007; revised 4/25/2007; accepted 4/27/2007. For correspondence or reprints contact: Wan-Yu Lin, M.D., Department of Medical Imaging, Taichung Veterans General Hospital. 160 Section 3, Taichung Harbor Road, Taichung 407, Taiwan. Tel: (886)4-23741349, Fax: (886)4-23741348, E-mail: wylin@ vghtc.gov.tw Langerhans’ cell histiocytosis (LCH) is a proliferative histiocytosis disorder. The...