BACKGROUND Hitherto, methicillin-resistant Staphylococcus aureus (MRSA) has not been detected in Swedish cattle. However, due to the report of mecC, a novel homologue to the mecA gene, there was reason to re-evaluate susceptibility results from strain collections of Staphylococcus aureus and test suspected isolates for the presence of mecC. FINDINGS Bovine isolates of S. aureus with elevated ...

The presence of antibiotic residues in water is linked to the emergence resistance globally and necessitates novel decontamination strategies minimize residue exposure both environment food. A holistic assessment cold atmospheric pressure plasma technology (CAPP) for β-lactam removal described this study. CAPP operating parameters including jet voltage, gas composition treatment time were optim...

The reductive amination/cyclization of biomass-based keto acids and amines to lactams under mild condition with ammonia borane (NH3–BH3) as the hydrogen donor in absence additives is reporte...

Methicillin-resistant Staphylococcus aureus (MRSA) has become the dominant strain of Staphylococcus aureus in many communities of the United States. As a result, many clinicians are now empirically covering for this pathogen in the treatment of various skin and soft-tissue infections. Should this practice apply to cellulitis? In order to answer this question, we defined cellulitis and reviewed ...

In general, the susceptibility of envelope mutants of Escherichia coli to beta-lactam compounds correlates well with the permeability of these antibiotics through the outer membrane. However, several mutants were isolated which, although apparently freely permeable to penicillins, showed only marginal increases in susceptibility to these agents.

Pseudomonas aeruginosa common surface antigens were compared in a permeability mutant (PCC118) and its parent (PAO503). The distribution of lipopolysaccharide and porin antigens in the mutant supports the conclusion that beta-lactam permeability was affected by lipopolysaccharide-side chain presentation rather than by a change in porin number.

A single-step catalytic ring expansion approach from 4-oxoazetidine-2-carbaldehydes to enantiopure succinimides has been achieved by the use of a base (DBU) and a thiazolium salt precatalyst.

Antimicrobial susceptibility was determined in 15 epidemiologically unrelated clinical isolates of Acinetobacter genospecies 3. Moreover, the mechanisms of resistance to some beta-lactam antibiotics may be associated with the presence of a chromosomal cephalosporinase, AmpC, and the resistance to quinolones related to mutations in the gyrA and parC genes.