Anion-exchange chromatography resolves human plasma low-density lipoprotein (LDL) into 5 subfractions, with increasing negative surface charge in the direction of L1 to L5. Unlike the harmless L1 to L4, the exclusively atherogenic L5 is rejected by the normal LDL receptor (LDLR) but endocytosed into vascular endothelial cells through the lectin-like oxidized LDL receptor-1 (LOX-1). Analysis wit...

OBJECTIVE This study aimed to investigate radiographic fusion rates at L4-5 and L5-S1 after single level posterior lumbar interbody fusion (PLIF) and evaluate the relationship between fusion rates and preoperative disc slope angle (DSA), lumbar lordosis (LL), segmental angle (SA), and pelvic parameters. METHODS We conducted a retrospective review of patients who underwent single level PLIF at...

purpose many factors such as lumbar instability and spinopelvic alignment are associated with low back pain. our purpose was to analyze the pelvic incidence - one of spinopelvic alignment parameters- and spine instability correlations in patients with chronic low back pain. methods fifty-two patients suffering from chronic low back pain entered this case control study. lateral spine radiography...

BACKGROUND The lumbosacral disc with the adjacent iliac crest and its relationships to neurologic, visceral, and vascular structures is difficult to approach with cannula-based retractor systems. Previous, less invasive approaches have been described to access this space. Anterior, presacral, and transforaminal approaches each have approach-related complications that have prevented their widesp...

BACKGROUND To assess the correlation between lumbar disc degeneration (LDD), multifidus muscle atrophy (LMA), and facet joints degeneration in patients with L4-L5 lumbar disc herniation (LDH). METHODS Sixty patients with L4-L5 LDH diagnosed by a 1.5 T MRI scanner were enrolled in the study group and another 60 patients with non-specific back pain were enrolled in the control group. LDD, LMA, ...

Glucocorticoids are widely prescribed to treat autoimmune and inflammatory diseases. Although they are extremely potent, their utility in clinical practice is limited by a variety of adverse side effects. Development of compounds that retain the potent immunomodulating and anti-inflammatory properties of classic glucocorticoids while exhibiting reduced adverse actions is therefore a priority. U...

In the present work, ribosomes assembled in bacterial cells in the absence of essential ribosomal protein L5 were obtained. After arresting L5 synthesis, Escherichia coli cells divide a limited number of times. During this time, accumulation of defective large ribosomal subunits occurs. These 45S particles lack most of the central protuberance (CP) components (5S rRNA and proteins L5, L16, L18,...

In [17], we introduced a modal logic, called L, which combines intuitionistic propositional logic IPC and classical propositional logic CPC and is complete w.r.t. an algebraic semantics. However, L seems to be too weak for Kripke-style semantics. In this paper, we add positive and negative introspection and show that the resulting logic L5 has a Kripke semantics. For intermediate logics I , we ...