Submit Manuscript | http://medcraveonline.com Abbreviations: OA: Osteoarthritis; TKA: Total Knee Arthroplasty; KOA: Knee Osteoarthritis; WOMAC: Western Ontario Master Universities; KOOS: Knee Injury Osteoarthritis Outcome Score; KSS: Knee Society Score; OKS: Oxford Knee Score; VAS: Visual Analogue Scale; CPM: Continuous Passive Motion; NMES: Neuromuscular Electrical Stimulation; ROM: Range of M...

Purpose: Total Knee Replacement (TKR) is the treatment of choice for severe osteoarthritis with acceptable outcomes regarding pain management, function and quality of life enhancement. Because many patients require TKR procedure for their both knees, there has always been a challenge in the choice of simultaneous or consecutive operations. The aim of the present study was to compare the t...

INTRODUCTION Symptomatic knee osteoarthritis (OA) is common. Advanced knee OA is successfully treated with joint replacement surgery, but effectively managing mild to moderate knee OA can be difficult. Angiogenesis increases with OA and might contribute to pain and structural damage. Modifying angiogenesis is a potential treatment pathway for OA. The aim of the current study is to determine whe...

OBJECTIVE To investigate the association between knee pain and signs of inflammation in the infrapatellar fat pad (IPFP) in obese patients with knee osteoarthritis (KOA). DESIGN In a cross-sectional setting, 3-T conventional contrast-enhanced (CE) magnetic resonance imaging (MRI) and dynamic contrast-enhanced (DCE)-MRI of KOA were analysed to quantify the extent of inflammation in the IPFP, a...

INTRODUCTION Viscosupplementation with hyaluronic acid (HA) of osteoarthritic (OA) knee joints has a well-established positive effect on clinical symptoms. This effect, however, is only temporary and the working mechanism of HA injections is not clear. It was suggested that HA might have disease modifying properties because of its beneficial effect on cartilage sulphated glycosaminoglycan (sGAG...

OBJECTIVE The prevalence of radiographic osteoarthritis (OA) after anterior cruciate ligament reconstruction (ACLR) approaches 50%, yet the prevalence of significant knee pain is unknown. We applied three different models of Knee injury and Osteoarthritis Outcome Score (KOOS) thresholds for significant knee pain to an ACLR cohort to identify prevalence and risk factors. DESIGN Multicenter Ort...

BACKGROUND Calcific deposits (CaDs) may be related to chronic postoperative pain and may affect function after patellar tendon surgery. STUDY DESIGN Cross-sectional. HYPOTHESIS We hypothesized that patients with CaDs (+CaDs) would rate lower than those without (-CaDs) on measures of knee function and quality of life. METHODS Patients completed the Tegner Lysholm Knee Scoring Scale (Lyshol...

BACKGROUND The benefits of exercise in mild and moderate knee or hip osteoarthritis (OA) are apparent, but the evidence in severe OA is less clear. We recently reported that neuromuscular training was well tolerated and feasible in patients with severe primary hip or knee OA. The aims of this controlled before-and-after study were to compare baseline status to an age-matched population-based re...

OBJECTIVE Matrix-associated autologous chondrocyte implantation has been used to treat cartilage defects. We developed a biphasic cylindrical osteochondral composite construct for such use, and conducted this study to determine its feasibility for treating osteochondral lesions in human knees. METHOD Ten patients with symptomatic osteochondral lesions at femoral condyles were treated by repla...

background: the present study aimed to translate and evaluate the reliability and validity of the persian version of the 11-item intermittent and constant osteoarthritis pain (icoap) measure in iranian subjects with knee osteoarthritis (koa). materials and methods: the icoap questionnaire was translated according to the manufacturers alliance for productivity and innovation (mapi) protocol. the...