Although news headlines and research dollars have focused largely on advances made in cancer treatments, prevention researchers are hard at work developing methods to stop cancer early — before it can even be called cancer. Lippman, professor of medicine and cancer prevention and chair of the Department of Clinical Cancer Prevention at the University of Texas M. D. Ander-son Cancer Center in Ho...

Squamous cell carcinoma (SCC) of the oral cavity is one most common malignancies head and neck. Risk factors for development SCC include infection with human papillomavirus (HPV), tobacco use, alcohol use. HPV-positive more commonly seen in young adult patients, whereas HPV-negative disease prevalent older patients histories We describe case a an extensive history vaping using nicotine-delivery...

BACKGROUND Among the numerous human papillomavirus (HPV) types, only types 16 and 18 have been formally classified as human carcinogens. To evaluate the associations of 33 HPV types and other risk factors with squamous cell carcinoma and adenocarcinoma of the cervix, we performed a hospital-based, case-control study in the Philippines. METHODS The study included 356 case subjects who had hist...

BACKGROUND Resistance to anticancer agents is a major obstacle for successful chemotherapy in tongue squamous cancer. Sam68 is an oncogenic-related protein in oral tongue squamous cell carcinoma functions as a signaling molecule mediating apoptosis, whose over-expression is associated with the clinicopathologic characteristics and prognosis of patients. The present study was to examine the effe...

The aim of this study is to investigate the effects of cold atmospheric pressure plasma (CAP)-induced radicals on the epidermal growth factor receptor (EGFR), which is overexpressed by oral squamous cell carcinoma, to determine the underlying mechanism of selective killing. CAP-induced highly reactive radicals were observed in both plasma plume and cell culture media. The selective killing effe...

OBJECTIVE To establish the time trends of the frequency and prevalence of oral cavity cancer in regard to age and gender in a 20-years (time period 1989 - 2008) cohort of Mexicans. DESIGN AND SETTING 13,235 head and neck biopsies from the archive of the Oral Pathology Laboratory, Dental School, National Autonomous University of Mexico were revised. The cases with diagnoses of oral cancer were...

OBJECTIVE To determine the outcome in patients with early squamous cell carcinoma of oral tongue, and the impact of various prognostic factors on survival. METHODS The retrospective study was conducted at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, and comprised records of patients treated for squamous cell carcinoma of early stage tongue between March 2003 ...

Giant cells are the soldiers of defensive system of our body. They differ based on the stimuli that provoked their formation. On the other hand, squamous cell carcinoma (SCC) being the most common oral cancer, presents with varied histopathological features based on the degree of differentiation. Keratinizing islands of dysplastic squamous epithelial cells & a dense inflammatory response form t...

Abstract—oral cavity cancer also called squamous cell carcinoma is the sixth most frequent overall, it a rising public health concern that spreading across globe. If not detected in earlier stages, might be severe generally, and underlying lesions induce it. Therefore, difficult to locate lesion area if cured its nascent reach stage IV cancer, metastatic stage. To come up with solution, we tend...