نتایج جستجو برای: kir3dl1

تعداد نتایج: 213  

2003
Peter Parham Joseph H. Phillips Lewis L. Lanier

Natural killer (NK) cells kill normal and transformed hematopoietic cells that lack expression of major histocompatibility complex (MHC) class I antigens. Lysis of HLA-negative Epstein Barr virus-transformed B lymphoblastoid call lines (B-LCL) by human NK cell clones can be inhibited by transfection of the target cells with certain HLA-A, -I3, or -C alleles. NK cell clones established from an i...

2017
A. Ruiz-Extremera E. J. Pavón-Castillero M. Florido P. Muñoz de Rueda J. A. Muñoz-Gámez J. Casado A. Carazo R. Quiles S. M. Jiménez-Ruiz A. Gila J. D. Luna J. León J. Salmerón

BACKGROUND & AIM There is evidence that maternal viral load of HCV during delivery influences the risk for Mother-to-child transmission (MTCT), but this does not explain all cases. We study the role of the immunogenetic profile (HLA, KIRs and KIR-ligand binding) of mothers and children in HCV-MTCT and in chronicity in the children. METHODOLOGY 79 HCV-RNA (+) mothers and their 98 children were...

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