objective: demyelination of cns axons occurs under pathological conditions such as multiple sclerosis and spinal cord injuries, but can be repaired by cell therapy. within the cns remyelination can be achieved by transplantation of neural stem cells (nscs). nscs are self-renewing cells that maintain the capacity to differentiate into cns-specific cell types and can differentiate into the three ...

cancer stem cells (csc) are the tumor-associated cells existed within tumors or hematological cancers which share characteristics similar to normal stem cells. the common characteristics of a normal stem cell and a csc are their differentiation capacity and self-renewal in tumors. the expression pattern of csc markers differs depending on the type and location of cancers. cd molecules are proba...

objective(s):some evidence showed that calcitriol has an important role in regulating growth and differentiation of mesenchymal stem cells (mscs). however, the interaction between mesenchymal stem cells and macrophage is not clear yet.  the current study was done to investigate the in vitro effects of calcitriol on the interactions between bone marrow-derived mscs and rat macrophages. materials...

backgrounds: a straight-forward way to identify whether a drug or environmental chemical can be harmful to unborn baby is to evaluate its effect on laboratory animals. all invivo methods need large number of animal and are therefore time consuming and expensive. however, the thousands of chemicals in need of testing, to reduce the spending of live animals, an assortment of in vitro assays has b...

Folia Biologica > Archive 2021, Vol. 67 Issue 4 Latent Defect in Haematopoiesis of… Fol. Biol. 67, 135-135 https://doi.org/10.14712/fb2021067040135 of UBC-GFP Mice Sheds Light on the Lymphoid Developmental Potential Haematopoietic Stem Cells Emanuel Nečas, K. Faltusová, C-L. Chen Institute Pathological Physiology, First Faculty Medicine, Charles University, Czech Republic Received November 2021...

0