Epilepsy is a neurological disorder characterized by unprovoked, recurring seizures that disrupt the nervous system and can cause mental and physical dysfunction. Based on the ethnopharmacological information of the plant, the methanol and aqueous extract of the whole plant of MELISSA OFFICINALIS was evaluated for its antiepileptic activity in Swiss Albino Mice .Antiepileptic activity was asses...

The aim of the present study was to evaluate hypnotic effect of Coriandrum sativum, Ziziphus jujuba, Lavandula angustifolia and Melissa officinalis hydroalcoholic extracts in mice to select the most effective ones for a combination formula. Three doses of the extracts (250, 500 and 1000 mg/kg of C. sativum and Z. jujuba and 200, 400 and 800 mg/kg of L. angustifolia and M. officinalis) were oral...

objectives the present study aimed to determine the effects of lemon balm alone and in combination with nepeta menthoides on menstrual bleeding in students with premenstrual syndrome. patients and methods this triple-blind randomized controlled trial included 93 female students with aged 18 years and older. the intervention groups received 500 mg capsules of lemon balm alone or lemon balm in co...

allelopathy refers to the chemical inhibition or stimulation of one species by another which could influence on the growth or germination of other plant and used in control of weed in agricultural practices. in this sense in order to study the possibly allelopathic effects of lemon balm, bitter apple and lemon verbena medicinal plants on control of wild mustard weed, a laboratory experiment was...

Despite advances in molecular biology and biology of tumors, in techniques for cancer detection or in the development of target directed compounds, the treatment of cancer is still a challenge. Thus, although some leukemias are now often curable and breast cancer became a chronic illness after treatment, the prognostic for other neoplasias remain poor. These tumors initially respond to chemothe...

Synergism between water, ethanol and ethyl acetate extract of Melissa officinalis and five commonly used antibiotics (streptomycin, chloramphenicol, tetracycline, amoxicillin, rifamycine) were investigated by disc diffusion method in relation to antibiotic-susceptible and antibiotic resistant human-pathogenic bacteria. The total phenol content in the extracts were determined by Folin-Ciocalteau...

objective: the aim of the present study was to investigate the neuroprotective effects of melissa officinalis, a major antioxidant plant, against neuron toxicity in hippocampal primary culture induced by 3,4-methylenedioxymethamphetamine (mdma) or ecstasy, one of the most abused drugs, which causes neurotoxicity. materials and methods: 3-(4,5-dimethyl-2 thiazoyl)-2,5-diphenyl-tetrazolium bromid...